What they do:
Decarbonizing the chemicals industry.
Quick facts:
HQ: Houston, TX, United States
Top Deep Tech Startups in Texas
This list has 50 startups and was last updated on Oct 15, 2026. 8 of them are hiring right now. Biggest hubs: Austin (24), Houston (15), and Fort Worth (2). Largest teams: Solugen, ElectroNeek, and UpEquity. Latest round: Novaspark Energy raised $156K (Oct 9, 2026).
50 startupsPage 1 of 2
What they do:
Robotic Process Automation and Document Processing Platform
Quick facts:
HQ: Austin, TX, United States
What they do:
UpEquity gives homebuyers more certainty and power.
Quick facts:
HQ: Austin, TX, United States
What they do:
Absorbable wrap for blood vessels
Quick facts:
HQ: Houston, TX, United States
Funding:
$10M · Debt · May 2026
What they do:
The shipping infrastructure of the internet.
Quick facts:
HQ: Austin, TX, United States
What they do:
Fetii is an AI-driven mobility platform
Quick facts:
HQ: Austin, TX, United States
UpCodes
Hiring
What they do:
AI platform for unifying codes, assemblies, products, and specs
Quick facts:
HQ: Austin, TX, United States
What they do:
Making all ships robots.
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HQ: Houston, TX, United States
Skyways
Hiring
What they do:
Creating a new form of air transportation to advance our civilization
Quick facts:
HQ: Austin, TX, United States
What they do:
Engineering the future of chemistry for natural resource extraction
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HQ: Austin, TX, United States
Handoff
Hiring
What they do:
AI estimator & agent for remodelers.
Quick facts:
HQ: Austin, TX, United States
9 Mothers
Hiring
What they do:
Counter Drone Systems. $1.6m sales. We delivered for the DoW.
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HQ: Austin, TX, United States
Drillbit
Hiring
What they do:
Automating Office Work for Residential Contractors.
Quick facts:
HQ: Austin, TX, United States
Tank Payments
Hiring
What they do:
Modern financial infrastructure for the trucking industry.
Quick facts:
HQ: Austin, TX, United States
What they do:
Computational antibody design
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HQ: Austin, TX, United States
What they do:
We deploy autonomous drones to 911 calls. Our software gives first…
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HQ: Houston, TX, United States
What they do:
Advanced Contract MFG for fast moving hardware companies
Quick facts:
HQ: Fort Worth, TX, United States
Perseus Defense
Hiring
What they do:
America's Golden Dome for Drones
Quick facts:
HQ: Austin, TX, United States
OctaPulse
Hiring
What they do:
Building the robotics layer for seafood production
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HQ: Frisco, TX, United States
What they do:
The dynamic single-cell analysis company
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HQ: Houston, TX, United States
What they do:
Helping physicians select the right therapy for breast cancer patients
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HQ: Austin, TX, United States
What they do:
AI Copilot for Property Managers and Landlords
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HQ: Austin, TX, United States
What they do:
US-Made Parts for Robots
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HQ: Austin, TX, United States
Quick facts:
HQ: Houston, TX, United States
Funding:
$100M · Equity · May 2026
Quick facts:
HQ: Houston, TX, United States
Funding:
$63M · Equity · May 2026
Quick facts:
HQ: Dallas, TX, United States
Funding:
$35M · Equity · Jun 2026
Quick facts:
HQ: Royse City, TX, United States
Incorporated: 2026
Funding:
$27M · Equity · May 2026
Quick facts:
HQ: Bellville, TX, United States
Incorporated: 2024
Funding:
$20.4M · Equity · May 2026
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HQ: Houston, TX, United States
Funding:
$18.6M · Equity · Sep 2026
Quick facts:
HQ: Euless, TX, United States
Incorporated: 2026
Funding:
$10M · Apr 2026
Quick facts:
HQ: Dallas, TX, United States
Incorporated: 2021
Funding:
$8.2M · Equity · Apr 2026
Quick facts:
HQ: Houston, TX, United States
Incorporated: 2023
Funding:
$7.7M · Debt · Jan 2026
Quick facts:
HQ: Austin, TX, United States
Incorporated: 2022
Funding:
$7.5M · Equity · Jun 2026
Quick facts:
HQ: College Station, TX, United States
Funding:
$5.72M · Equity · Jan 2026
Quick facts:
HQ: Houston, TX, United States
Incorporated: 2025
Funding:
$5.13M · Equity · Oct 2026
Quick facts:
HQ: Houston, TX, United States
Incorporated: 2026
Funding:
$4.45M · Equity · May 2026
Questions and answers
How many startups are on this list?
There are 50 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
8 of them are hiring right now, including UpCodes, Skyways, and Handoff.
Which of them have the largest teams?
By team size: Solugen (200 employees), ElectroNeek (175 employees), and UpEquity (90 employees).
Which of them raised money recently?
Latest rounds: Novaspark Energy — $156K Equity (Oct 2026), TMNTec — $5.13M Equity (Oct 2026), and Apogee Semiconductor — $1.5M Equity (Sep 2026).
Where are they based?
The biggest hubs are Austin (24), Houston (15), and Fort Worth (2).