What they do:
Enterprise-grade AI for revenue assurance
Quick facts:
HQ: San Francisco, CA, United States
Top Digital Health Startups in the United States
This list has 336 startups and was last updated on Oct 15, 2026. 100 of them are hiring right now. Biggest hubs: San Francisco (190), New York (67), and Boston (13). Largest teams: Truepill, Clipboard, and Athelas. Latest round: Atmos Clinic raised $6M (Oct 8, 2026).
336 startupsPage 2 of 10
Sully
Hiring
What they do:
Autonomous team of AI agents that runs the entire hospital operations
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Patient engagement for low-income populations
Quick facts:
HQ: Austin, TX, United States
Kivo Health
Hiring
What they do:
AI-powered care for seniors with chronic disease
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI Scribe for veterinarians. Saving time and improving patient care.
Quick facts:
HQ: Seattle, WA, United States
Lucira Health
Public
What they do:
Next generation infectious disease test kits
Quick facts:
HQ: Emeryville, CA, United States
SimplyInsured
Hiring
What they do:
We sell health insurance to small businesses 100% online.
Quick facts:
HQ: San Francisco, CA, United States
Mednet
Hiring
What they do:
Mednet helps doctors answer their toughest clinical questions —…
Quick facts:
HQ: New York, NY, United States
Reframe
Hiring
What they do:
App to help people quit or cut back on alcohol use
Quick facts:
HQ: Atlanta, GA, United States
Codes Health
Hiring
What they do:
Medical Record Retrieval with Zero Human Error
Quick facts:
HQ: New York, NY, United States
Bunkerhill Health
Hiring
What they do:
Bunkerhill is a long-horizon agent for health systems
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Legacy helps you test, improve, and freeze your sperm
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HQ: New York, NY, United States
Ankr Health
Hiring
What they do:
Virtualizing brick-mortar infrastructures of clinics w/ generative AI
Quick facts:
HQ: Houston, TX, United States
Metriport
Hiring
What they do:
Healthcare data infrastructure for next generation care delivery.
Quick facts:
HQ: San Francisco, CA, United States
Fortuna Health
Hiring
What they do:
TurboTax for Medicaid
Quick facts:
HQ: New York, NY, United States
Axle Health
Hiring
What they do:
Scheduling and workforce management SaaS for home healthcare providers
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Real-World Data for Health Innovation
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HQ: San Francisco, CA, United States
What they do:
We work with governments to implement telemedicine programs.
Quick facts:
HQ: Charleston, SC, United States
What they do:
Empowering women. Period.
Quick facts:
HQ: San Francisco, CA, United States
Terra API
Hiring
What they do:
API for developers and AIs to access health data
Quick facts:
HQ: San Francisco, CA, United States
mdhub
Hiring
What they do:
AI-native operating system for behavioral health clinics.
Quick facts:
HQ: San Francisco, CA, United States
Apero Health
Hiring
What they do:
Modern medical billing
Quick facts:
HQ: San Francisco, CA, United States
ArchForm
Hiring
What they do:
Replacing orthodontic braces with our clear aligner and software
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Modern, AI-powered clinical trial software platform.
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HQ: Fort Lauderdale, FL, United States
What they do:
Rare Disease-Focused Care Delivery and Evidence Generation Platform
Quick facts:
HQ: Claymont, DE, United States
What they do:
Just-in-time training and communication for frontline healthcare teams
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HQ: San Francisco, CA, United States
What they do:
Automated tooth cutting for dentists using imaging, AI and robotics
Quick facts:
HQ: Boston, MA, United States
Serif Health
Hiring
What they do:
Healthcare Price Transparency APIs and Data Products
Quick facts:
HQ: Los Angeles, CA, United States
Medplum
Hiring
What they do:
API first electronic health record (EHR) that is open source
Quick facts:
HQ: San Francisco, CA, United States
Pasito
Hiring
What they do:
AI agents for insurance and benefits
Quick facts:
HQ: New York, NY, United States
AgileMD
Hiring
What they do:
Predictive analytics and clinical pathways for hospitals
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Rest is an AI sleep coach that helps you fix your sleep for good,…
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HQ: San Francisco, CA, United States
Probably Genetic
Hiring
What they do:
Patient Intelligence Platform for Genetic Disease
Quick facts:
HQ: San Francisco, CA, United States
Arini
Hiring
What they do:
The single platform to run all healthcare operations
Quick facts:
HQ: San Francisco, CA, United States
What they do:
“One Medical for pets.”
Quick facts:
HQ: San Francisco, CA, United States
Clarion
Hiring
What they do:
The AI communication layer for healthcare
Quick facts:
HQ: New York, NY, United States