What they do:
Platform for breakthrough mental health research and treatment
Quick facts:
HQ: San Francisco, CA, United States
Top Healthcare Startups in California
This list has 551 startups and was last updated on Oct 15, 2026. 112 of them are hiring right now. Biggest hubs: San Francisco (419), Los Angeles (22), and San Diego (20). Largest teams: Gusto, Truepill, and Clipboard. Latest round: Renue Life Sciences raised $250K (Oct 14, 2026).
551 startupsPage 2 of 16
Latent
Hiring
What they do:
Medical language models to automate healthcare operations
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Enterprise-grade AI for revenue assurance
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HQ: San Francisco, CA, United States
Sully
Hiring
What they do:
Autonomous team of AI agents that runs the entire hospital operations
Quick facts:
HQ: San Francisco, CA, United States
Living Carbon
Hiring
What they do:
maximizing biomass on low quality land
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HQ: San Francisco, CA, United States
Kivo Health
Hiring
What they do:
AI-powered care for seniors with chronic disease
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HQ: San Francisco, CA, United States
Lucira Health
Public
What they do:
Next generation infectious disease test kits
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HQ: Emeryville, CA, United States
SimplyInsured
Hiring
What they do:
We sell health insurance to small businesses 100% online.
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HQ: San Francisco, CA, United States
What they do:
We grow cells for biotech companies.
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HQ: San Francisco, CA, United States
Bunkerhill Health
Hiring
What they do:
Bunkerhill is a long-horizon agent for health systems
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HQ: San Francisco, CA, United States
Metriport
Hiring
What they do:
Healthcare data infrastructure for next generation care delivery.
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HQ: San Francisco, CA, United States
Synthio Labs
Hiring
What they do:
Agentic AI platform for Pharma GTM teams
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HQ: San Francisco, CA, United States
Axle Health
Hiring
What they do:
Scheduling and workforce management SaaS for home healthcare providers
Quick facts:
HQ: Los Angeles, CA, United States
Vitalize
Hiring
What they do:
Transforming how health systems optimize labor
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HQ: San Francisco, CA, United States
What they do:
Real-World Data for Health Innovation
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HQ: San Francisco, CA, United States
What they do:
Empowering women. Period.
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HQ: San Francisco, CA, United States
Terra API
Hiring
What they do:
API for developers and AIs to access health data
Quick facts:
HQ: San Francisco, CA, United States
What they do:
CRISPR powered Diagnostics with results in minutes.
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HQ: San Diego, CA, United States
Invert
Hiring
What they do:
Data analytics software for biomanufacturing.
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HQ: San Francisco, CA, United States
mdhub
Hiring
What they do:
AI-native operating system for behavioral health clinics.
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HQ: San Francisco, CA, United States
Ember
Hiring
What they do:
AI RCM. Increase net revenue by 16%.
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HQ: San Francisco, CA, United States
Apero Health
Hiring
What they do:
Modern medical billing
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HQ: San Francisco, CA, United States
What they do:
AI Powered Animal Diagnostics
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HQ: San Francisco, CA, United States
What they do:
Replika is an AI friend that you can talk to designed to make you…
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HQ: San Francisco, CA, United States
What they do:
Targeting Cancer with Click Chemistry
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HQ: San Francisco, CA, United States
ArchForm
Hiring
What they do:
Replacing orthodontic braces with our clear aligner and software
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HQ: San Francisco, CA, United States
Datrics
Hiring
What they do:
Generative AI Healthcare Coding Automation
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HQ: San Francisco, CA, United States
What they do:
Just-in-time training and communication for frontline healthcare teams
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HQ: San Francisco, CA, United States
What they do:
Enabling next generation medicines. A comprehensive platform and…
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HQ: San Francisco, CA, United States
Serif Health
Hiring
What they do:
Healthcare Price Transparency APIs and Data Products
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HQ: Los Angeles, CA, United States
Parallel Bio
Hiring
What they do:
Using the immune system to cure disease
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HQ: San Francisco, CA, United States
Medplum
Hiring
What they do:
API first electronic health record (EHR) that is open source
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HQ: San Francisco, CA, United States
Readily
Hiring
What they do:
AI Compliance Platform for Healthcare Organizations
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HQ: San Francisco, CA, United States
Tamarind Bio
Hiring
What they do:
AI Inference Platform for Drug Discovery
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HQ: San Francisco, CA, United States
AgileMD
Hiring
What they do:
Predictive analytics and clinical pathways for hospitals
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HQ: San Francisco, CA, United States
What they do:
Rest is an AI sleep coach that helps you fix your sleep for good,…
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HQ: San Francisco, CA, United States