What they do:
Patreon for AI Originals
Quick facts:
HQ: San Francisco, CA, United States
Top Startups in San Francisco
This list has 3,173 startups and was last updated on Oct 15, 2026. 784 of them are hiring right now. Largest teams: DoorDash, Stripe, and Airbnb. Latest round: Modal raised $750M (Oct 14, 2026).
3,173 startupsPage 42 of 89
What they do:
AI-native pharma company
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-Native FDA Regulatory Services
Quick facts:
HQ: San Francisco, CA, United States
What they do:
A personal or team assistant that works while you sleep
Quick facts:
HQ: San Francisco, CA, United States
What they do:
agents for the rest of us
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We help lawyers start and scale AI-native law firms.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The AI-native contact center
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Watch and create anime
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The market behind AI hardware.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Building a neutral, sovereign alternative to Starlink
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Making chemicals 100,000x faster
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Reliable and safe data engineering and data science agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Build everyday back-office agents on one live model of your books
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Organizing company knowledge
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Infrastructure for building and scaling AI-native businesses.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-native test infrastructure layer for hardware companies
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The social trading app for stocks, memes, and perps
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Oura Ring for Skin
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The identity and communication layer for AI agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Turns real businesses into robotics data vendors
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We find flaws in RL environments and evals and help you fix them.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Florin is an AI-native insurance company that runs autonomously
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Internal industrial company data for frontier labs
Quick facts:
HQ: San Francisco, CA, United States
What they do:
RL post-training for science reasoning and performance engineering
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Autoresearch as a service: we solve your hardest measurable problems
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Evals for robots
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Model Agnostic AI coworker in Slack
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Wet lab infrastructure that turns AI experiments into training data.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
See and control what your agents actually do
Quick facts:
HQ: San Francisco, CA, United States
What they do:
An AI-operated logistics company.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Embodied Scientific Intelligence
Quick facts:
HQ: San Francisco, CA, United States
What they do:
An AI bracelet that remembers your day and acts before you ask.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Motor cortex for physical AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Continuous optimization for AI agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
100% automated inspection for consumer electronics parts
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The managed cloud for AI agents.
Quick facts:
HQ: San Francisco, CA, United States