Plexe
Hiring
What they do:
Open-source agents to build predictive ML models from a prompt
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HQ: London, United Kingdom
Top Startups in the United Kingdom
This list has 247 startups and was last updated on Oct 15, 2026. 59 of them are hiring right now. Biggest hubs: London (217), Oxford (5), and Manchester (4). Largest teams: GoCardless, LemFi, and Permutive. Latest round: Obsero raised €1M (Oct 13, 2026).
247 startupsPage 4 of 7
What they do:
The AI Associate for Litigation Lawyers
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HQ: London, United Kingdom
PRINCEPS
Hiring
What they do:
AI-native insurance company for the compute economy
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HQ: London, United Kingdom
What they do:
Accounting software that works for you
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HQ: London, United Kingdom
What they do:
Employee benefit for reproductive and hormone health
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HQ: London, United Kingdom
What they do:
Search engine for trustworthy medical information.
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HQ: London, United Kingdom
What they do:
Voice AI for Automotive
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HQ: London, United Kingdom
What they do:
AI Agents for Advisory & Financial Services.
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HQ: London, United Kingdom
What they do:
Understand why your AI agent breaks. Iterate fast to fix it.
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HQ: London, United Kingdom
What they do:
The fastest & most scalable graph-vector database on the market
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HQ: London, United Kingdom
Sparkles
Hiring
What they do:
Make everyone on your team an engineer
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HQ: London, United Kingdom
What they do:
We help you find and book tickets to great entertainment events that…
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HQ: London, United Kingdom
QuestDB
Hiring
What they do:
Data platform for mission-critical real-time workloads
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HQ: London, United Kingdom
YC S20Early stage
Minimum
Hiring
What they do:
Helping corporates achieve Net Zero through tech solutions.
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HQ: London, United Kingdom
YC S20Early stage
What they do:
The multicurrency account and card for Brazilians
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HQ: London, United Kingdom
What they do:
The super app for pets
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HQ: London, United Kingdom
What they do:
We help high-growth startups go viral on autopilot
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HQ: London, United Kingdom
What they do:
Simple tests for complex diseases.
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HQ: London, United Kingdom
What they do:
Generate, iterate, and ship AI ad creatives faster
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HQ: London, United Kingdom
What they do:
Deliver genes to any cell with AI
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HQ: London, United Kingdom
What they do:
AI Employees who love overtime
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HQ: London, United Kingdom
What they do:
Humanoid robots that do your chores for the price of an iPhone!
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HQ: London, United Kingdom
What they do:
AI Report Generation for Engineering & Environmental Review
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HQ: London, United Kingdom
What they do:
Building lunar landers
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HQ: London, United Kingdom
What they do:
Programmable DNA drug destroying all cancers, unlocking 80% of targets
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HQ: Oxford, United Kingdom
What they do:
The mid-market agent platform
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HQ: London, United Kingdom
What they do:
AI agents for power grid planning 🦑
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HQ: London, United Kingdom
Zymbly
Hiring
What they do:
The decision-support layer for aviation ops teams to know what to do…
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HQ: London, United Kingdom
YC W26Early stage
What they do:
AI Scheduling for Short Haul Trucks
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HQ: London, United Kingdom
What they do:
Turns spreadsheets into internal apps and customer portals
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HQ: London, United Kingdom
What they do:
Transforming pharmacies in the UK into diagnostic centers
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HQ: London, United Kingdom
What they do:
Get data insights without writing SQL
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HQ: London, United Kingdom
What they do:
Financial intelligence for every investor
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HQ: London, United Kingdom
What they do:
Unlock wasted GPU capacity.
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HQ: London, United Kingdom
What they do:
Office management software for hybrid workspaces
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HQ: London, United Kingdom
What they do:
High-performance gloves for VR and AR
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HQ: London, United Kingdom