What they do:
Make diesel semi trucks hybrid-electric
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HQ: San Francisco, CA, United States
Top Logistics Startups in California
This list has 159 startups and was last updated on Oct 15, 2026. 38 of them are hiring right now. Biggest hubs: San Francisco (137) and Los Angeles (18). Largest teams: GrubMarket, Instacart, and Flexport. Latest round: Numerion Labs raised $19.8M (Mar 19, 2026).
159 startupsPage 3 of 5
What they do:
The world's first AI-maximalist pharma company
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HQ: San Francisco, CA, United States
What they do:
Operational Intelligence for Global Logistics
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HQ: San Francisco, CA, United States
What they do:
Evolutionary intelligence for autoimmune disease
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HQ: San Francisco, CA, United States
What they do:
AI-native procurement services for the physical economy
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HQ: San Francisco, CA, United States
What they do:
Unmanned cargo airplanes
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HQ: Los Angeles, CA, United States
What they do:
Automating away manual admin for food distributors: texts to ERP
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HQ: San Francisco, CA, United States
What they do:
Last-mile delivery for perishables.
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HQ: San Francisco, CA, United States
What they do:
Growing micro-organs to find new drugs
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HQ: San Francisco, CA, United States
What they do:
Truckload Planning at Machine Precision
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HQ: San Francisco, CA, United States
What they do:
Autonomous operations for industrial distributors
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HQ: San Francisco, CA, United States
What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
An AI-operated logistics company.
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HQ: San Francisco, CA, United States
What they do:
Fastest, easiest, and most affordable way for small business owners…
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HQ: San Francisco, CA, United States
What they do:
Synkrino's AI, SATIS is a powerful, unbiased discovery system for…
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HQ: San Francisco, CA, United States
What they do:
Menten AI designs peptide and protein therapeutics using quantum…
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HQ: San Francisco, CA, United States
What they do:
Build factory ready tech packs in minutes.
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HQ: Los Angeles, CA, United States
What they do:
Single source of truth for your clinic's finances and supply chain.
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HQ: San Francisco, CA, United States
What they do:
Making procurement easy
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HQ: San Francisco, CA, United States
What they do:
Multimodal foundation models to predict uncollected patient biology
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HQ: San Francisco, CA, United States
What they do:
AI teammates for logistics
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HQ: San Francisco, CA, United States
What they do:
Automating dexterous tasks in warehouses with AI-powered robots
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HQ: San Francisco, CA, United States
What they do:
FDE as a platform for rebuilding critical operations in software.
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HQ: San Francisco, CA, United States
What they do:
Building AI Native Customs Brokerages
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HQ: San Francisco, CA, United States
What they do:
Drop-in robotic labor that works on Day 1
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HQ: Los Angeles, CA, United States
What they do:
AI-powered freight brokerage. Quote, book, and track loads in seconds.
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HQ: San Francisco, CA, United States
What they do:
AI-native freight brokerage
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HQ: San Francisco, CA, United States
What they do:
AI Operating System for Wholesale Distribution
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HQ: San Francisco, CA, United States
What they do:
Curing cancer. Starting with dogs.
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HQ: San Francisco, CA, United States
What they do:
AI Brokers for Industrial Trade
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HQ: San Francisco, CA, United States
What they do:
AI for the industries that power America.
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HQ: San Francisco, CA, United States
What they do:
Precision navigation for UAVs operating without GPS.
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HQ: San Francisco, CA, United States
What they do:
The AI decision engine for factories, warehouses and fleets
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HQ: San Francisco, CA, United States
What they do:
Lark - AI agents that automate workflows for wholesale distributors
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HQ: San Francisco, CA, United States
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Perlara: building the YC for rare disease parents
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HQ: San Francisco, CA, United States
What they do:
Multi-agent AI for physical logistics operations
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HQ: San Francisco, CA, United States