
What they do:
AI-powered technology enabler and digital transformer of American…
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HQ: San Francisco, CA, United States
This list has 233 startups and was last updated on Oct 15, 2026. 65 of them are hiring right now. Biggest hubs: San Francisco (137), New York (34), and Los Angeles (18). Largest teams: GrubMarket, Instacart, and Flexport. Latest round: Fleet Response Ultimate Parent raised $10M (Apr 10, 2026).

What they do:
AI-powered technology enabler and digital transformer of American…
Quick facts:
HQ: San Francisco, CA, United States

What they do:
Marketplace for grocery delivery and pickup
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HQ: San Francisco, CA, United States

What they do:
Platform for global logistics.
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HQ: San Francisco, CA, United States

What they do:
Our operations software makes it easier to run--and grow--your cafe
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HQ: New York, NY, United States

What they do:
Providing Amazon level logistics to e-commerce businesses.
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HQ: Chicago, IL, United States

What they do:
We break viruses
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HQ: San Francisco, CA, United States

What they do:
Nabis is the largest licensed cannabis wholesale platform.
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HQ: New York, NY, United States

What they do:
Self-driving semi trucks.
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HQ: San Francisco, CA, United States

What they do:
The everything app for LATAM
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HQ: Los Angeles, CA, United States

What they do:
Powering the animal health supply chain.
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HQ: Miami, FL, United States

What they do:
Artificial intelligence for drug discovery.
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HQ: San Francisco, CA, United States
Funding:
$19.8M · Equity · Mar 2026

What they do:
Making car ownership and management frictionless.
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HQ: Nashville, TN, United States

What they do:
Construction & industrial logistics platform.
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HQ: Los Angeles, CA, United States

What they do:
Your AI partner for North America truckload freight
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HQ: New York, NY, United States

What they do:
Intelligence that runs your operations.
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HQ: San Francisco, CA, United States

What they do:
Modernizing global transportation payments.
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HQ: San Francisco, CA, United States

What they do:
Mason is the fastest way to take smart devices from idea to end user
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HQ: Seattle, WA, United States

What they do:
BeGo Connects cargo shippers with truck suppliers in Mexico and US
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HQ: San Francisco, CA, United States

What they do:
We verify global supply chains for issues like child slavery and…
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HQ: New York, NY, United States

What they do:
Move anything, anytime, anywhere
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HQ: Salt Lake City, UT, United States

What they do:
We use human data and AI to develop better drugs faster.
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HQ: San Francisco, CA, United States

What they do:
The shipping infrastructure of the internet.
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HQ: Austin, TX, United States

What they do:
The operating system powering ecommerce fulfillment
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HQ: Los Angeles, CA, United States

What they do:
Healthy packaged fresh food
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HQ: Los Angeles, CA, United States

What they do:
Medicinal Chemistry powered by Machine Learning
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HQ: Boston, MA, United States

What they do:
Nash is the digital logistics infrastructure for commerce
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HQ: San Francisco, CA, United States

What they do:
Automation platform for logistics
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HQ: San Francisco, CA, United States

What they do:
Laundry & Dry Cleaning delivered.
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HQ: New York, NY, United States

What they do:
The automated solution for complex freight transactions.
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HQ: Los Angeles, CA, United States

What they do:
Making all ships robots.
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HQ: Houston, TX, United States

What they do:
We're making ecommerce simple connecting brands with sales channels
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HQ: Columbia, MD, United States

What they do:
Shopify for vehicles
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HQ: New York, NY, United States

What they do:
AI-Native Fresh Produce Logistics
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HQ: San Francisco, CA, United States

What they do:
Scheduling and workforce management SaaS for home healthcare providers
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HQ: Los Angeles, CA, United States

What they do:
Autonomous drones to help warehouses scan inventory.
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HQ: San Francisco, CA, United States

What they do:
Targeting Cancer with Click Chemistry
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HQ: San Francisco, CA, United States
There are 233 startups on this list, last updated on Oct 15, 2026.
65 of them are hiring right now, including Instacart, Flexport, and Odeko.
By team size: GrubMarket (4,548 employees), Instacart (3,000 employees), and Flexport (3,000 employees).
Latest rounds: Fleet Response Ultimate Parent — $10M (Apr 2026), Numerion Labs — $19.8M Equity (Mar 2026), and G2 Reverse Logistics — $1.5M Debt (Mar 2026).
The biggest hubs are San Francisco (137), New York (34), and Los Angeles (18).