What they do:
Nervous System for Physical AI
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HQ: San Francisco, CA, United States
Top Manufacturing Startups in San Francisco
This list has 223 startups and was last updated on Oct 15, 2026. 65 of them are hiring right now. Largest teams: Bellabeat, Human Archive, and Ansa Biotechnologies. Latest round: Multiply Labs raised $75M (Oct 7, 2026).
223 startupsPage 4 of 7
What they do:
AI-native procurement services for the physical economy
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HQ: San Francisco, CA, United States
What they do:
Robots for high skilled labor powering AI infrastructure
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HQ: San Francisco, CA, United States
What they do:
Real-time cloud inference for robotics.
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HQ: San Francisco, CA, United States
What they do:
Enable robots to operate safely in the real world.
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HQ: San Francisco, CA, United States
What they do:
The Data Platform for Mission‑Critical Systems
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HQ: San Francisco, CA, United States
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AI chips for ultra-fast training and inference
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HQ: San Francisco, CA, United States
What they do:
Foundation Model for Chemical Manufacturing
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HQ: San Francisco, CA, United States
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Batteries and solar for $0 upfront to help businesses save money
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HQ: San Francisco, CA, United States
What they do:
Gigascale Nanomanufacturing
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HQ: San Francisco, CA, United States
What they do:
Datadog for industrial robots
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HQ: San Francisco, CA, United States
What they do:
Robots that repair roads
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HQ: San Francisco, CA, United States
What they do:
We assemble PCBs in under 48 hours for quantities under 10
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HQ: San Francisco, CA, United States
What they do:
AI for the physical world
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HQ: San Francisco, CA, United States
What they do:
Digital transformation for real economy businesses
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HQ: San Francisco, CA, United States
What they do:
Large-scale real-world robot & human data for embodied AI
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HQ: San Francisco, CA, United States
What they do:
Building the Data Infrastructure layer for Physical AI.
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HQ: San Francisco, CA, United States
What they do:
Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States
What they do:
Evals for robots
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HQ: San Francisco, CA, United States
What they do:
Embodied Scientific Intelligence
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HQ: San Francisco, CA, United States
What they do:
An AI bracelet that remembers your day and acts before you ask.
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HQ: San Francisco, CA, United States
What they do:
100% automated inspection for consumer electronics parts
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HQ: San Francisco, CA, United States
What they do:
The Self-Hosting Company
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HQ: San Francisco, CA, United States
What they do:
Datadog for robots
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HQ: San Francisco, CA, United States
What they do:
AI-native remote operations center for hardware fleets
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HQ: San Francisco, CA, United States
What they do:
Physics-based foundation models for CAD optimization.
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HQ: San Francisco, CA, United States
What they do:
Building tiny frontier AI models that run on edge devices
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HQ: San Francisco, CA, United States
What they do:
AI-Native Data Center Engineering
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HQ: San Francisco, CA, United States
What they do:
Waymo for excavators
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HQ: San Francisco, CA, United States
What they do:
AI-native ERP for manufacturers
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HQ: San Francisco, CA, United States
What they do:
The robot workforce for infrastructure
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HQ: San Francisco, CA, United States
What they do:
Automating dexterous tasks in warehouses with AI-powered robots
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HQ: San Francisco, CA, United States
What they do:
AI that runs factories.
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HQ: San Francisco, CA, United States
What they do:
Research lab building the most robotic household in the world
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HQ: San Francisco, CA, United States
What they do:
Humanoid robot platform for builders.
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HQ: San Francisco, CA, United States
What they do:
Control lab instruments with natural language.
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HQ: San Francisco, CA, United States