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Top Medtech Startups in California

This list has 63 startups and was last updated on Oct 15, 2026. 13 of them are hiring right now. Biggest hubs: San Francisco (49), Los Angeles (6), and San Diego (2). Largest teams: BillionToOne, Eden, and Spire Health. Latest round: Ventaris Surgical raised $30.7M (Mar 2, 2026).

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Questions and answers

How many startups are on this list?

There are 63 startups on this list, last updated on Oct 15, 2026.

Which of them are hiring?

13 of them are hiring right now, including Notable Labs, BillionToOne, and Eden.

Which of them have the largest teams?

By team size: BillionToOne (300 employees), Eden (100 employees), and Spire Health (52 employees).

Which of them raised money recently?

Latest rounds: Ventaris Surgical — $30.7M Equity (Mar 2026).

Where are they based?

The biggest hubs are San Francisco (49), Los Angeles (6), and San Diego (2).