
Spire Health
What they do:
Remote patient monitoring for lung disease patients.
Quick facts:
HQ: San Francisco, CA, United States
This list has 63 startups and was last updated on Oct 15, 2026. 13 of them are hiring right now. Biggest hubs: San Francisco (49), Los Angeles (6), and San Diego (2). Largest teams: BillionToOne, Eden, and Spire Health. Latest round: Ventaris Surgical raised $30.7M (Mar 2, 2026).

What they do:
Remote patient monitoring for lung disease patients.
Quick facts:
HQ: San Francisco, CA, United States

What they do:
Smartphone-enabled, at-home diagnostics
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HQ: Los Angeles, CA, United States

What they do:
Novel long-read DNA sequencing technology
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HQ: San Francisco, CA, United States

What they do:
Wearables and AI to predict and prevent sepsis outside the hospital
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HQ: San Francisco, CA, United States

What they do:
Devices to improve the quality of life for people with Spinal Cord…
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HQ: San Clemente, CA, United States

What they do:
Using cooling to end brain damage during stroke.
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HQ: San Francisco, CA, United States

What they do:
Implantable microchips and AI for cattle monitoring
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HQ: San Francisco, CA, United States

What they do:
Radiology in the cloud. X-rays, CAT scans, MRI's, and…
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HQ: San Francisco, CA, United States
What they do:
Bringing 3rd generation, nanopore sequencing to healthcare to solve…
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HQ: San Francisco, CA, United States

What they do:
Next-gen blood testing to provide 1000x more data to pharma companies
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HQ: San Francisco, CA, United States

What they do:
Medinas helps hospitals manage their inventory and buy and sell their…
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HQ: San Francisco, CA, United States

What they do:
Klarismo turns your body into an interactive experience. We built a…
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HQ: San Francisco, CA, United States

What they do:
Testing & treatment at home, in minutes, for chronic & acute disease
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HQ: San Francisco, CA, United States

What they do:
Buid, test and deploy perception applications
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HQ: San Francisco, CA, United States

What they do:
At-home blood testing: measure + analyze + enhance.
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HQ: San Francisco, CA, United States

What they do:
Rapid, scalable diagnostic for SARS-CoV-2 and beyond
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HQ: San Francisco, CA, United States

What they do:
We cure intractable leg wounds with a replacement valve for veins.
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HQ: San Francisco, CA, United States

What they do:
Discover drugs that control how much cells "squeeze" to treat disease
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HQ: Los Angeles, CA, United States

What they do:
Hearing aids that work in noisy places, like restaurants, using ML.
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HQ: San Francisco, CA, United States

What they do:
Breaking new ground in online eyecare.
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HQ: San Francisco, CA, United States

What they do:
Transforming the lives of millions of women suffering from chronic…
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HQ: San Clemente, CA, United States

What they do:
Nano-diamonds for cancer detection
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HQ: San Francisco, CA, United States

What they do:
Low-cost blood glucose test strips scanned with a smartphone camera…
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HQ: San Francisco, CA, United States

What they do:
Immediate stroke detection at home
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HQ: San Francisco, CA, United States

What they do:
One-time, device-based treatment for heart failure
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HQ: San Francisco, CA, United States

What they do:
Volt Health is developing medical devices that deliver electrical…
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HQ: San Francisco, CA, United States
What they do:
Low cost consumer device for toxin detection.
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HQ: San Francisco, CA, United States