What they do:
Early detection of Alzheimer's disease
Quick facts:
HQ: San Francisco, CA, United States
Top Medtech Startups in the United States
This list has 117 startups and was last updated on Oct 15, 2026. 19 of them are hiring right now. Biggest hubs: San Francisco (49), Boston (9), and New York (8). Largest teams: Ginkgo Bioworks, BillionToOne, and Opentrons. Latest round: Curadel Surgical Innovations raised $49.8M (Oct 13, 2026).
117 startupsPage 2 of 4
What they do:
Portable cryoablation to prevent cervical cancer
Quick facts:
HQ: San Francisco, CA, United States
Floracene
Hiring
What they do:
Vibecode + deploy HIPAA-compliant internal tools, no eng team needed
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HQ: New York, NY, United States
What they do:
Responsive materials, better lives.
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HQ: Los Angeles, CA, United States
What they do:
We built the world's first automated digital pathology lab.
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HQ: Houston, TX, United States
What they do:
XGenomes is building the sequencing technology of the future.
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HQ: Boston, MA, United States
What they do:
AI-designed Affinity Reagents
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HQ: Austin, TX, United States
Haplotype Labs
Hiring
What they do:
Personalized prevention using genetics and AI
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HQ: San Francisco, CA, United States
What they do:
Cancer tests based on whole genome and transcriptome data.
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HQ: New York, NY, United States
What they do:
One-hour antibiotic sensitivity testing
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HQ: Baltimore, MD, United States
What they do:
AI enabling digital urine diagnostics in the home
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HQ: Houston, TX, United States
What they do:
High-precision, closed-loop neuromodulation devices
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HQ: Boston, MA, United States
What they do:
Gen-AI Designed Enzymes for Pharmaceutical Innovation
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HQ: Boston, MA, United States
What they do:
Our tests help eradicate cancer by telling doctors whether they got…
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HQ: San Francisco, CA, United States
What they do:
Helping Plastic Surgeons Rebuild Fat
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HQ: Durham, NC, United States
What they do:
Semi-Autonomous Diagnostics for Emergent Care
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HQ: FL, United States
What they do:
Natural hydrogel to keep internal organs scar-free after surgery
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HQ: Houston, TX, United States
What they do:
Catheter-based solution to treat chronic heart failure.
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HQ: Houston, TX, United States
What they do:
Helping physicians select the right therapy for breast cancer patients
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HQ: Austin, TX, United States
What they do:
Neurostimulation implant to restore hearing & speech understanding
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HQ: San Francisco, CA, United States
What they do:
Reinventing respiration monitoring
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HQ: Los Angeles, CA, United States
What they do:
AI Diagnosis of Heart Disease
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HQ: San Francisco, CA, United States
What they do:
CRM Co-Pilot for Medtech Sales
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HQ: San Francisco, CA, United States
What they do:
Higher resolution MRI with faster scan times.
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HQ: New York, NY, United States
What they do:
Converting biology into digital molecular maps
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HQ: Philadelphia, PA, United States
What they do:
Redefining the Standard of Care for Iron Deficiency Anemia
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HQ: San Francisco, CA, United States
What they do:
Next-Generation Surgical Navigation and Robotics
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HQ: Boston, MA, United States
YC S19Early stage
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HQ: Bonita Springs, FL, United States
Funding:
$49.8M · Equity + debt · Oct 2026
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HQ: San Carlos, CA, United States
Incorporated: 2024
Funding:
$30.7M · Equity · Mar 2026
Quick facts:
HQ: Reno, NV, United States
Incorporated: 2021
Funding:
$20.9M · Equity + debt · Jun 2026
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HQ: New York, NY, United States
Incorporated: 2023
Funding:
$18.2M · Equity · Mar 2026
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HQ: Portsmouth, NH, United States
Funding:
$14.4M · Feb 2026
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HQ: Baltimore, MD, United States
Incorporated: 2022
Funding:
$11.2M · Equity · Apr 2026
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HQ: Birmingham, AL, United States
Funding:
$7.4M · Equity · Feb 2026
Quick facts:
HQ: Winter Park, FL, United States
Incorporated: 2026
Funding:
$4.4M · Equity · Jun 2026
Quick facts:
HQ: Westbury, NY, United States
Incorporated: 2023
Funding:
$3.65M · Equity · May 2026