What they do:
AI-designed Affinity Reagents
Quick facts:
HQ: Austin, TX, United States
Top Machine Learning Startups
This list has 243 startups and was last updated on Oct 15, 2026. 72 of them are hiring right now. Biggest hubs: San Francisco (128), New York (30), and London (11). Largest teams: Cruise, Relativity Space, and Flock Safety.
243 startupsPage 4 of 7
What they do:
Create custom NLP models
Quick facts:
HQ: Boston, MA, United States
What they do:
Developing long-lasting drug formulations 50% faster
Quick facts:
HQ: Sacramento, CA, United States
Rimward
Hiring
What they do:
Solar farm security software for existing cameras
Quick facts:
What they do:
We make robots that move boxes in warehouses
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-powered demand forecasting for retail
Quick facts:
What they do:
Artificial Intuition for marketing
Quick facts:
HQ: San Francisco, CA, United States
Sift
Hiring
What they do:
The Leader in Digital Trust & Safety
Quick facts:
HQ: San Francisco, CA, United States
What they do:
iPhone-based driver monitoring for commercial fleets.
Quick facts:
HQ: San Francisco, CA, United States
Deepnote
Hiring
What they do:
A better data science notebook.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Helping a billion people build their dream career
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Student Attendance tracking for Public Schools
Quick facts:
HQ: Dallas, TX, United States
What they do:
AI enabling digital urine diagnostics in the home
Quick facts:
HQ: Houston, TX, United States
What they do:
Trade with superhuman instinct
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Scale AI scientists whose own breakthroughs accelerate the next.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Shiru leverages ML to create proteins to feed the world sustainably.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The dynamic single-cell analysis company
Quick facts:
HQ: Houston, TX, United States
What they do:
Classify Anything
Quick facts:
HQ: CA, United States
What they do:
Serverless Infrastructure Platform for AI
Quick facts:
HQ: New York, NY, United States
What they do:
Dataset Management for AI Trainers
Quick facts:
HQ: New York, NY, United States
What they do:
Don't die of heart disease. Empirical is the first AI-native heart…
Quick facts:
HQ: New York, NY, United States
What they do:
Foundation models to automate x-ray analysis for radiologists
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We sell GPUs.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI powered brokerage reducing residential rental commissions in NYC…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI English Tutor
Quick facts:
HQ: New York, NY, United States
What they do:
A search technology that actually finds what you’re looking for.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The AI platform for CRE investment teams
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Infrastructure for managing GPU clusters for training/serving.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Specialized AI for Critical Industries
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We find flaws in RL environments and evals and help you fix them.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Autoresearch as a service: we solve your hardest measurable problems
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Discover novel defense related materials/molecules.
Quick facts:
HQ: Haifa, Israel
What they do:
An AI-operated logistics company.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
100% automated inspection for consumer electronics parts
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Product recommendations.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Open-source monitoring for machine learning models
Quick facts:
HQ: London, United Kingdom