What they do:
AI Fitness Coach
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HQ: San Francisco, CA, United States
Top Wellness Startups in the United States
This list has 207 startups and was last updated on Oct 15, 2026. 40 of them are hiring right now. Biggest hubs: San Francisco (121), New York (27), and Boston (5). Largest teams: Truepill, Clipboard, and Noora Health. Latest round: Aspira Women's Health raised $1.49M (Jun 22, 2026).
207 startupsPage 4 of 6
What they do:
AI health coach in your pocket
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HQ: New York, NY, United States
What they do:
24/7 Personal Health & Longevity Companion
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HQ: San Francisco, CA, United States
What they do:
AI nutrition coach in your pocket
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HQ: San Francisco, CA, United States
What they do:
Oura Ring for Skin
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HQ: San Francisco, CA, United States
What they do:
mRNA therapeutics to extend healthspan entering clinical trials
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HQ: San Francisco, CA, United States
What they do:
23andMe for environmental exposures
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HQ: San Francisco, CA, United States
What they do:
Enabling Tissue Targeting of Therapies
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HQ: San Francisco, CA, United States
What they do:
AI Accountability Partner
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HQ: New York, NY, United States
What they do:
Automating nutrition tracking.
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HQ: San Francisco, CA, United States
What they do:
Get Paid for Family Caregiving
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HQ: Dover, DE, United States
What they do:
ML to predict and prevent pregnancy complications
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HQ: San Diego, CA, United States
What they do:
AI relationship app that keeps couples together
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HQ: San Francisco, CA, United States
What they do:
Mobile app helping people better manage chronic health conditions
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HQ: San Francisco, CA, United States
What they do:
AI physical therapy for athletes
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HQ: San Francisco, CA, United States
What they do:
Genetically engineered viruses that teach your immune system to kill…
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HQ: San Francisco, CA, United States
What they do:
A Disease Focused Biotech, Building Multiple Billion Dollar Drugs
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HQ: San Francisco, CA, United States
What they do:
Scaling Genomic AI for Embryo Selection
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HQ: Boston, MA, United States
What they do:
Voice AI for medical language translation
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HQ: San Francisco, CA, United States
What they do:
The health coach that texts you first
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HQ: San Francisco, CA, United States
What they do:
AI EMR for medspas & wellness clinics
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HQ: New York, NY, United States
What they do:
Financial infrastructure for family caregiving
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HQ: San Francisco, CA, United States
What they do:
World's Earliest Test for Alzheimer's Biomarkers
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HQ: San Francisco, CA, United States
What they do:
Pelvic floor fitness made easy
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HQ: Chicago, IL, United States
What they do:
Helps build social skills through daily practice
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HQ: San Francisco, CA, United States
What they do:
Making low cost versions of high cost generic drugs.
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HQ: Dallas, TX, United States
YC S18Early stage
What they do:
Proactive Testing and Treatments
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HQ: New York, NY, United States
YC W22Early stage
What they do:
Home medical equipment, prescribed online and delivered.
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HQ: Seattle, WA, United States
YC S21Early stage
What they do:
AI operating system for veterinary care
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HQ: San Francisco, CA, United States
YC W24Early stage
NURX
Acquired
What they do:
Medicine or testing kit, prescribed online and delivered to your door.
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HQ: New York, NY, United States
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HQ: Long Island City, NY, United States
Funding:
$9.86M · Equity · Feb 2026
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HQ: Lewes, DE, United States
Incorporated: 2025
Funding:
$8M · Equity · Mar 2026
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HQ: Austin, TX, United States
Incorporated: 2024
Funding:
$7.15M · Equity · Apr 2026
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HQ: Portland, OR, United States
Funding:
$7M · Equity · Jun 2026
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HQ: Towson, MD, United States
Incorporated: 2021
Funding:
$5.27M · Equity · Feb 2026
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HQ: Harvard, IL, United States
Incorporated: 2025
Funding:
$5M · Equity · Jun 2026