What they do:
the AI coding app for thinking.
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HQ: San Francisco, CA, United States
Top AI Agent Startups in California
This list has 159 startups and was last updated on Oct 15, 2026. 56 of them are hiring right now. Biggest hubs: San Francisco (151) and Los Angeles (7). Largest teams: Daily, Broccoli AI, and Weekend (fmr. Volley). Latest round: Copilot Labs, Inc. \ DE raised $21.2M (Jan 23, 2026).
159 startupsPage 4 of 5
What they do:
AI agents for insurance claims
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HQ: San Francisco, CA, United States
What they do:
Open source agentic BI for founders
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HQ: San Francisco, CA, United States
What they do:
Your email assistant because you deserve a better morning
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HQ: San Francisco, CA, United States
What they do:
Orca lets you build, discover, and play Minecraft games with friends.
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HQ: San Francisco, CA, United States
What they do:
The complete, collaborative workspace for humans and agents
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HQ: Los Angeles, CA, United States
What they do:
AWS for AI Agents
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HQ: San Francisco, CA, United States
What they do:
AI agents that help you understand your customers' needs
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HQ: San Francisco, CA, United States
What they do:
The Cursor for Chip Design - Delivering Silicon-Ready Chip Designs…
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HQ: San Francisco, CA, United States
What they do:
Planet-scale people discovery.
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HQ: San Francisco, CA, United States
What they do:
TikTok for Sports Trading
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HQ: San Francisco, CA, United States
What they do:
A proactive desktop copilot. Clippy, but actually good.
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HQ: San Francisco, CA, United States
What they do:
The first Agentic platform for Oncology
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HQ: San Francisco, CA, United States
What they do:
AI Employees for Primary Care
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HQ: San Francisco, CA, United States
What they do:
We help software companies get discovered and used by AI agents
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HQ: San Francisco, CA, United States
What they do:
Agentic operating system for auto repair shops
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HQ: San Francisco, CA, United States
What they do:
Staging Environments for Enterprise AI Agents
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HQ: San Francisco, CA, United States
What they do:
Specialized models that make your AI agents cheaper and more reliable.
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HQ: San Francisco, CA, United States
What they do:
Your personal context, securely portable across every AI app.
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HQ: San Francisco, CA, United States
What they do:
Duolingo for learning anything
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HQ: San Francisco, CA, United States
What they do:
Training Data For Speech Models.
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HQ: San Francisco, CA, United States
What they do:
Multi-agent AI for physical logistics operations
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HQ: San Francisco, CA, United States
What they do:
ChatGPT's memory feature in an open, portable format
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HQ: San Francisco, CA, United States
What they do:
The tiny computer built for voice AI.
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HQ: San Francisco, CA, United States
What they do:
AI agent that manages manufacturing operations over text
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HQ: San Francisco, CA, United States
What they do:
Camera-free AI glasses. Your AI, out in the world.
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HQ: San Francisco, CA, United States
What they do:
Random labs is building long running autonomous coding agents.
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HQ: San Francisco, CA, United States
YC S24Early stage
What they do:
AI Employee for Manufacturing Operations
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HQ: San Francisco, CA, United States
YC X26Early stage
What they do:
cards for AI agents
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HQ: San Francisco, CA, United States
YC S26Early stage
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HQ: San Francisco, CA, United States
Incorporated: 2024
Funding:
$21.2M · Equity · Jan 2026
Command AI
Acquired
What they do:
AI-powered user assistance platform
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HQ: San Francisco, CA, United States
Truva
Acquired
What they do:
Sell more. Grind less with AI agents.
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HQ: San Francisco, CA, United States
DeepSource
Acquired
What they do:
Unified DevSecOps platform, helping developers ship good code.
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HQ: San Francisco, CA, United States
Clear Genetics
Acquired
What they do:
Clear Genetics is scaling delivery of Genomic services
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HQ: San Francisco, CA, United States
Brewit
Acquired
What they do:
Conversational data analytics for every team
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HQ: San Francisco, CA, United States
Hey Revia
Acquired
What they do:
Voice AI to automate complex phone calls for healthcare providers
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HQ: San Francisco, CA, United States