Ginkgo Bioworks
HiringPublic
What they do:
Our mission is to make biology easier to engineer.
Quick facts:
HQ: Boston, MA, United States
Top Deep Tech Startups in Massachusetts
This list has 49 startups and was last updated on Oct 15, 2026. 6 of them are hiring right now. Biggest hubs: Boston (38), Cambridge (3), and Waltham (2). Largest teams: Ginkgo Bioworks, Raptor Maps, and SiPhox Health. Latest round: Finwave Semiconductor raised $15.5M (Oct 8, 2026).
49 startupsPage 1 of 2
What they do:
Raptor Maps builds software to manage the solar PV lifecycle.
Quick facts:
HQ: Boston, MA, United States
SiPhox Health
Hiring
What they do:
At-Home health monitoring with silicon photonic chips for data centers
Quick facts:
HQ: Boston, MA, United States
Volta Labs, Inc.
Hiring
What they do:
Unlocking the utility of genomics for the world.
Quick facts:
HQ: Boston, MA, United States
PostEra
Hiring
What they do:
Medicinal Chemistry powered by Machine Learning
Quick facts:
HQ: Boston, MA, United States
What they do:
Automated tooth cutting for dentists using imaging, AI and robotics
Quick facts:
HQ: Boston, MA, United States
What they do:
AI-native Robotics
Quick facts:
HQ: Boston, MA, United States
What they do:
Next-generation mRNA platform to solve cancer, COVID and climate.
Quick facts:
HQ: Boston, MA, United States
What they do:
Data integration & insights for state and local governments
Quick facts:
HQ: Boston, MA, United States
Pirouette Pharma
Hiring
What they do:
We make injections as easy as pushing a button!
Quick facts:
HQ: Boston, MA, United States
What they do:
Ravn is building a heads-up display for soldiers.
Quick facts:
HQ: Boston, MA, United States
What they do:
Patent-pending enzymes to break down common dietary triggers
Quick facts:
HQ: Boston, MA, United States
What they do:
We use AI to design antibodies for intractable diseases
Quick facts:
HQ: Boston, MA, United States
What they do:
Plaid for Commercial Real Estate
Quick facts:
HQ: Boston, MA, United States
What they do:
Making 'REAL' Cow and Human Milk!
Quick facts:
HQ: Boston, MA, United States
What they do:
Gen-AI Designed Enzymes for Pharmaceutical Innovation
Quick facts:
HQ: Boston, MA, United States
What they do:
Metal manufacturing, faster, cheaper, and more versatile.
Quick facts:
HQ: Boston, MA, United States
What they do:
Using DNA to store data.
Quick facts:
HQ: Boston, MA, United States
What they do:
USA-made magnetics for robotics and defense.
Quick facts:
HQ: Boston, MA, United States
What they do:
Robotic Training Data at Scale
Quick facts:
HQ: Boston, MA, United States
What they do:
Robots for the inspection and maintenance of data centers
Quick facts:
HQ: Boston, MA, United States
What they do:
Life sciences reagents and software
Quick facts:
HQ: Boston, MA, United States
What they do:
The fully autonomous intelligence layer in the sky.
Quick facts:
HQ: Boston, MA, United States
What they do:
The Intelligence layer for Drug Manufacturing
Quick facts:
HQ: Boston, MA, United States
What they do:
Infrastructure Cartography
Quick facts:
HQ: Boston, MA, United States
What they do:
Next-Generation Surgical Navigation and Robotics
Quick facts:
HQ: Boston, MA, United States
YC S19Early stage
What they do:
AI-controlled optical switching for AI clusters
Quick facts:
HQ: Boston, MA, United States
YC S26Early stage
What they do:
We make the most compact nuclear reactors
Quick facts:
HQ: Boston, MA, United States
YC X26Early stage
Quick facts:
HQ: Boston, MA, United States
Funding:
$180M · Equity · Apr 2026
Quick facts:
HQ: Cambridge, MA, United States
Funding:
$24M · Equity · Jan 2026
Quick facts:
HQ: Waltham, MA, United States
Funding:
$16.9M · Equity · Oct 2026
Quick facts:
HQ: Waltham, MA, United States
Funding:
$15.5M · Equity · Oct 2026
Quick facts:
HQ: Cambridge, MA, United States
Incorporated: 2024
Funding:
$14.6M · Equity · Mar 2026
Quick facts:
HQ: Wellesley, MA, United States
Incorporated: 2026
Funding:
$7M · Equity · Apr 2026
Quick facts:
HQ: Charlestown, MA, United States
Incorporated: 2022
Funding:
$5.4M · Options · Feb 2026
Quick facts:
HQ: Harvard, MA, United States
Funding:
$4.82M · Equity · Apr 2026
Questions and answers
How many startups are on this list?
There are 49 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
6 of them are hiring right now, including Ginkgo Bioworks, SiPhox Health, and Volta Labs, Inc.
Which of them have the largest teams?
By team size: Ginkgo Bioworks (641 employees), Raptor Maps (75 employees), and SiPhox Health (63 employees).
Which of them raised money recently?
Latest rounds: Finwave Semiconductor — $15.5M Equity (Oct 2026), Adden Energy — $16.9M Equity (Oct 2026), and River Otter Renewables — $759K Debt (Oct 2026).
Where are they based?
The biggest hubs are Boston (38), Cambridge (3), and Waltham (2).