Top AI Startups in San Francisco

99 employeesYC S18Early stage14 open roles

Applied AI & ML Developer tools

Momentic

Hiring

What they do:

Mo, the AI QA engineer that bug-bashes your app before every release

Quick facts:

18 employeesYC W24Early stage4 open roles

Funding:

$18.6M · Equity · Jan 2026

Applied AI & ML IoT & telecom

Ridecell

Hiring

What they do:

World's Leading Fleet Intelligence Platform

Quick facts:

88 employeesYC W12Growth stage

Applied AI & ML Developer tools Data & analytics

Airbyte

What they do:

Context layer for production-grade AI agents

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90 employeesYC W20Early stage

Applied AI & ML AI agents & assistants Real estate & construction

Broccoli AI

Hiring

What they do:

AI-native operating system for home service businesses

Quick facts:

85 employeesYC W22Growth stage

Legal, compliance & gov Applied AI & ML Payments

Promise

Hiring

What they do:

Better payment systems for governments and the communities they serve.

Quick facts:

80 employeesYC W18Growth stage11 open roles

Applied AI & ML Gaming AI agents & assistants Media & entertainment

Weekend (fmr. Volley)

Hiring

What they do:

AI games and entertainment on TV

Quick facts:

80 employeesYC W18Growth stage

Logistics & supply chain AI agents & assistants Applied AI & ML

HappyRobot

Hiring

What they do:

Intelligence that runs your operations.

Quick facts:

80 employeesYC S23Growth stage

Applied AI & ML Accounting & finance ops

Fondo

What they do:

Bookkeeping, tax, & tax credits on autopilot for 2,000+ startups

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80 employeesYC W18Early stage

Applied AI & ML Cloud & infrastructure Media & entertainment

Tavus

Hiring

What they do:

Building the human layer of AI

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75 employeesYC S21Growth stage18 open roles

Pump.co

Hiring

What they do:

The Costco for cloud is here 🔥🔥

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75 employeesYC S22Early stage

Cybersecurity Applied AI & ML Developer tools

ZeroPath

What they do:

Automatically find and fix your software vulnerabilities

Quick facts:

10 employeesYC S24Early stage

Funding:

$7.03M · SAFE · Mar 2026

Biotech & pharma Applied AI & ML

Altay Therapeutics

What they do:

Altay develops disease-modifying therapies targeting transcription…

Quick facts:

6 employeesYC W20Early stage

Funding:

$15.7M · Equity · Oct 2026

Applied AI & ML Developer tools

Veryfi, Inc.

Hiring

What they do:

Document AI. One API Call.

Quick facts:

70 employeesYC W17Growth stage

Real estate & construction Applied AI & ML

VergeSense

Hiring

What they do:

AI-Powered Building Management

Quick facts:

70 employeesYC S17Growth stage2 open roles

Developer tools Applied AI & ML

Exa

What they do:

Web search rebuilt for LLMs

Quick facts:

75 employeesYC S21Growth stage

Applied AI & ML Productivity & automation

Motion

Hiring

What they do:

The only work management platform for both Human and AI Employees

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65 employeesYC W20Growth stageRemote

Logistics & supply chain Applied AI & ML Banking & lending Investing & wealth

BeGo

Hiring

What they do:

BeGo Connects cargo shippers with truck suppliers in Mexico and US

Quick facts:

65 employeesYC W20Early stage

Real estate & construction Applied AI & ML

Cambio

Hiring

What they do:

AI-native commercial real estate operations

Quick facts:

60 employeesYC S22Growth stage7 open roles

Legal, compliance & gov Applied AI & ML

Flagright

Hiring

What they do:

AI-native AML compliance platform for fintechs & banks

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58 employeesYC W22Early stage11 open roles

Applied AI & ML Cloud & infrastructure

Mireye

What they do:

Search Engine for the Physical World

Quick facts:

2 employeesYC S26Early stage

Funding:

$1.01M · Equity · Sep 2026

Legal, compliance & gov Applied AI & ML

Datasaur

What they do:

Datasaur builds private AI/agents for enterprise/government

Quick facts:

60 employeesYC W20Early stageRemote

Applied AI & ML E-commerce & retail AI agents & assistants

BIK

Hiring

What they do:

Agentic AI CRM for ecommerce

Quick facts:

55 employeesYC S20Growth stageRemote

Applied AI & ML Sales & marketing

Recurrency

Hiring

What they do:

Automated ERP for distributors.

Quick facts:

50 employeesYC S20Growth stage

Luminai

Hiring

What they do:

Luminai is the AI platform for Health System Operations.

Quick facts:

50 employeesYC S20Growth stage17 open roles

Vapi

Hiring

What they do:

Voice AI for developers.

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50 employeesYC W21Growth stage24 open roles

Real estate & construction Applied AI & ML

Agave

Hiring

What they do:

Applied AI for Construction

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50 employeesYC W22Early stage10 open roles

Applied AI & ML Insurance Digital health & care

Latent

Hiring

What they do:

Medical language models to automate healthcare operations

Quick facts:

50 employeesYC W23Early stage24 open roles

Applied AI & ML AI agents & assistants Productivity & automation Sales & marketing

Artisan

Hiring

What they do:

AI employees that take on real work, starting with sales

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50 employeesYC W24Growth stage4 open roles

Retell AI

Hiring

What they do:

Supercharge Your Contact Center Operations with AI Phone Agents

Quick facts:

50 employeesYC W24Early stage27 open roles

Applied AI & ML AI agents & assistants AI infrastructure & models

Domu Technology Inc.

Hiring

What they do:

AI Agents for collections

Quick facts:

50 employeesYC S24Growth stage

Sales & marketing Applied AI & ML

LeadGenius

What they do:

LeadGenius is an account-based marketing and lead generation…

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50 employeesYC S11Growth stage

Education Applied AI & ML

Ello

Hiring

What they do:

Building the world's first 1:1 AI teacher.

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45 employeesYC W20Early stage4 open roles

Robotics & drones Food & agriculture Applied AI & ML Manufacturing & chips

Hedgehog

What they do:

Building robotic mushroom farms

Quick facts:

50 employeesYC S22Early stage

Applied AI & ML Accounting & finance ops

TaxGPT

Hiring

What they do:

AI tax assistant for professionals and businesses

Quick facts:

45 employeesYC S24Early stage

Applied AI & ML Productivity & automation Digital health & care

Sully

Hiring

What they do:

Autonomous team of AI agents that runs the entire hospital operations

Quick facts:

44 employeesYC S21Early stage