
Locke
What they do:
The AI-native firm for public influence.
Quick facts:
HQ: San Francisco, CA, United States
This list has 1,958 startups and was last updated on Oct 15, 2026. 632 of them are hiring right now. Biggest hubs: San Francisco (1,355), New York (312), and Los Angeles (47). Largest teams: Cruise, Relativity Space, and Podium. Latest round: Agriculture Scout AI raised $425K (Oct 13, 2026).

What they do:
The AI-native firm for public influence.
Quick facts:
HQ: San Francisco, CA, United States

What they do:
AI-Native Medical Group for Mental Health
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HQ: San Francisco, CA, United States

What they do:
App that turns selfie photos into thousand emoji that look like you…
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HQ: San Francisco, CA, United States

What they do:
AI to curate your baby photos
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HQ: San Francisco, CA, United States

What they do:
Language models for enterprise applications.
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HQ: Los Angeles, CA, United States

What they do:
Analyze, act, and automate across systems
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HQ: New York, NY, United States

What they do:
Your AI co-worker
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HQ: San Francisco, CA, United States

What they do:
Making fast food faster
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HQ: Los Angeles, CA, United States

What they do:
Programmable biology company for psychoactive effect design
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HQ: San Francisco, CA, United States

What they do:
Automating procurement and finance for construction companies
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HQ: New York, NY, United States

What they do:
AI for product formulation
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HQ: San Francisco, CA, United States

What they do:
Restaurant Loyalty Using Quiz
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HQ: San Francisco, CA, United States

What they do:
AI Models for GIS
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HQ: San Francisco, CA, United States

What they do:
Founder-level assistance whenever customers need it, at scale
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HQ: San Francisco, CA, United States

What they do:
Recover failed subscription payments to increase retention and LTV
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HQ: Boston, MA, United States

What they do:
Automate support ops natively in Slack
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HQ: New York, NY, United States

What they do:
Generative AI for administrative automation in healthcare
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HQ: San Francisco, CA, United States

What they do:
Reimagining education with short form video and AI
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HQ: New York, NY, United States

What they do:
Manage a swarm of AI agents to get real work done
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HQ: San Francisco, CA, United States

What they do:
Cloud platform for coding agents
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HQ: New York, NY, United States

What they do:
AI-enabled procurement for government
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HQ: New York, NY, United States

What they do:
Give Your Employee An Employee
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HQ: San Francisco, CA, United States

What they do:
AI coach for your entire life
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HQ: San Francisco, CA, United States

What they do:
Healthcare personal assistants for Medicare patients.
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HQ: New York, NY, United States

What they do:
An AI physics simulator for AI chip design
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HQ: San Francisco, CA, United States

What they do:
Artificial Intelligence for your medical billing team
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HQ: San Francisco, CA, United States

What they do:
Automatic AI Legal Diligence
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HQ: San Francisco, CA, United States

What they do:
Chips for frontier AI
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HQ: San Francisco, CA, United States

What they do:
AI for Legal & Public Policy Teams
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HQ: Washington, DC, United States

What they do:
Candle helps friends and couples grow closer daily in just 5 minutes.
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HQ: San Francisco, CA, United States

What they do:
The Localization Engineering Platform
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HQ: San Francisco, CA, United States

What they do:
AI Operating System for Pre-construction
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HQ: San Francisco, CA, United States

What they do:
The multiplayer control plane for your software factory
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HQ: San Francisco, CA, United States

What they do:
The AI Growth Engine for Industrials
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HQ: San Francisco, CA, United States

What they do:
Outbound voice and text AI without a prompt
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HQ: New York, NY, United States

What they do:
AI for Commercial Insurance Agencies
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HQ: Seattle, WA, United States