Thirdlayer
Hiring
What they do:
Continual learning for enterprise AI
Quick facts:
HQ: San Francisco, CA, United States
Top AI Startups in the United States
This list has 1,958 startups and was last updated on Oct 15, 2026. 632 of them are hiring right now. Biggest hubs: San Francisco (1,355), New York (312), and Los Angeles (47). Largest teams: Cruise, Relativity Space, and Podium. Latest round: Agriculture Scout AI raised $425K (Oct 13, 2026).
1,958 startupsPage 22 of 55
Chestnut
Hiring
What they do:
The first AI mortgage lender
Quick facts:
HQ: San Francisco, CA, United States
Ralo
Hiring
What they do:
AI-Native Mortgage Broker
Quick facts:
HQ: New York, NY, United States
What they do:
Specialized AI for Every Job
Quick facts:
HQ: San Francisco, CA, United States
Alkali
Hiring
What they do:
The smarter way to estimate steel.
Quick facts:
HQ: Houston, TX, United States
MangoDesk
Hiring
What they do:
Long-horizon RL environments
Quick facts:
HQ: San Francisco, CA, United States
Humwork
Hiring
What they do:
Human experts as API for AI Agents
Quick facts:
HQ: San Francisco, CA, United States
CareSwift
Hiring
What they do:
AI scribe for Ambulance Reports
Quick facts:
HQ: New York, NY, United States
Wedge
Hiring
What they do:
AI Employees for Healthcare
Quick facts:
HQ: San Francisco, CA, United States
OneStop
Hiring
What they do:
The local internet for NYC.
Quick facts:
HQ: New York, NY, United States
OS3
Hiring
What they do:
Affordable, intelligent humanoid robots built to deploy at scale
Quick facts:
HQ: San Francisco, CA, United States
Flick
Hiring
What they do:
We Handle AI. You Direct Films.
Quick facts:
HQ: Santa Barbara, CA, United States
Alder
Hiring
What they do:
AI employees for finance, starting with accounts receivable.
Quick facts:
HQ: San Francisco, CA, United States
Unsiloed AI
Hiring
What they do:
API for parsing multimodal unstructured data
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Robotic factories that build robots
Quick facts:
HQ: Emeryville, CA, United States
Lemma
Hiring
What they do:
Production Monitoring for AI agents
Quick facts:
HQ: San Francisco, CA, United States
Layers
Hiring
What they do:
Improve your appearance by measuring, understanding, and tracking…
Quick facts:
HQ: San Francisco, CA, United States
Waddle Labs
Hiring
What they do:
LLMs that control robots
Quick facts:
HQ: San Francisco, CA, United States
Payna
Hiring
What they do:
AI Licensing Agent for Regulated Industries
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-native workspace for AEC
Quick facts:
HQ: San Francisco, CA, United States
Salus
Hiring
What they do:
Guardrails to validate your agent's actions before they execute
Quick facts:
HQ: San Francisco, CA, United States
Ventura
Hiring
What they do:
AI Workforce for Distributors and Manufacturers
Quick facts:
HQ: San Francisco, CA, United States
Fenrock AI
Hiring
What they do:
AI agents for banks
Quick facts:
HQ: San Francisco, CA, United States
Chasi
Hiring
What they do:
AI Revenue Engine for the Equipment Industry
Quick facts:
HQ: San Francisco, CA, United States
Tsenta
Hiring
What they do:
AI career agent that finds matching jobs & applies on your behalf
Quick facts:
HQ: San Francisco, CA, United States
Hedge
Hiring
What they do:
AI-Native insurance company
Quick facts:
HQ: San Francisco, CA, United States
Discovered Materials
Hiring
What they do:
AI scientists to discover materials for the semiconductor industry.
Quick facts:
HQ: San Francisco, CA, United States
Uno Wallet
Hiring
What they do:
The AI mobile wallet that replaces Apple Pay
Quick facts:
HQ: San Francisco, CA, United States
flowscope
Hiring
What they do:
AI implementation firm that maps and automates business processes
Quick facts:
HQ: San Francisco, CA, United States
Parasma
Hiring
What they do:
Replacing GPUs with human brain cells
Quick facts:
HQ: San Francisco, CA, United States
Rex
Hiring
What they do:
AI-native BPO for enterprise order-to-cash
Quick facts:
HQ: San Francisco, CA, United States
Synapse Semiconductor
Hiring
What they do:
New semiconductors that merge compute and vision
Quick facts:
HQ: Durham, NC, United States
IMPACT Drones
Hiring
What they do:
Air Defense as a Service for Civilian Infrastructure.
Quick facts:
HQ: San Francisco, CA, United States
Marble
Hiring
What they do:
The autonomous back-of-house for restaurants.
Quick facts:
HQ: New York, NY, United States
screenpipe
Hiring
What they do:
Turn your company's computer work into AI agents.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI collections agency for late stage portfolios
Quick facts:
HQ: San Francisco, CA, United States