What they do:
Your personal context, securely portable across every AI app.
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HQ: San Francisco, CA, United States
Top B2B Software Startups in California
This list has 2,349 startups and was last updated on Oct 15, 2026. 592 of them are hiring right now. Biggest hubs: San Francisco (2,110), Los Angeles (79), and San Diego (12). Largest teams: Stripe, Deel, and GrubMarket. Latest round: Modal raised $750M (Oct 14, 2026).
2,349 startupsPage 38 of 66
What they do:
Crafting simulations for frontier lab model training
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HQ: San Francisco, CA, United States
What they do:
The autonomous AI model factory
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HQ: San Francisco, CA, United States
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AI FDE that deploys custom AI agents into ERPs
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HQ: San Francisco, CA, United States
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Making Diamond Semiconductors
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HQ: San Francisco, CA, United States
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Simulating Agents Running Industrial Companies
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HQ: San Francisco, CA, United States
What they do:
Accurately simulate market response at scale
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HQ: San Francisco, CA, United States
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A cloud devbox that feels local
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HQ: San Francisco, CA, United States
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Self-optimizing neocloud that cuts LLM costs by 100x
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HQ: San Francisco, CA, United States
What they do:
AI Agents to Make Local Gov Efficient
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HQ: San Francisco, CA, United States
What they do:
Foundation models on enterprise transaction data.
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HQ: San Francisco, CA, United States
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AI-native OS for Real Estate Brokerages
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HQ: San Francisco, CA, United States
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OpenClaw for manufacturers
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HQ: San Francisco, CA, United States
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Defining the frontier of multiplayer AI.
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HQ: San Francisco, CA, United States
What they do:
Market for future inference capacity
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HQ: San Francisco, CA, United States
What they do:
AI-powered freight brokerage. Quote, book, and track loads in seconds.
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HQ: San Francisco, CA, United States
What they do:
CrowdStrike for AI Agents
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HQ: San Francisco, CA, United States
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Quant Neolab building self-improving agents from quant data
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HQ: San Francisco, CA, United States
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AI-native freight brokerage
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HQ: San Francisco, CA, United States
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AI for Construction's Back Office
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HQ: San Francisco, CA, United States
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AI Operating System for Wholesale Distribution
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HQ: San Francisco, CA, United States
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Databricks for Enterprise Codebases
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HQ: San Francisco, CA, United States
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Legora for AEC (Architecture, Engineering, & Construction) firms
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HQ: San Francisco, CA, United States
What they do:
The world's frontier hacker of AI agents.
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HQ: San Francisco, CA, United States
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Legora for commercial insurance carriers
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HQ: San Francisco, CA, United States
What they do:
AI-Native Insurance for Frontier Tech
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HQ: San Francisco, CA, United States
What they do:
Predict how market participants behave
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HQ: San Francisco, CA, United States
What they do:
Industrial Controllers built for AI
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HQ: Los Angeles, CA, United States
What they do:
AI native platform for real estate closings
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HQ: San Francisco, CA, United States
What they do:
We find where AI agents fail, then train better models to run them.
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HQ: San Francisco, CA, United States
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The AI-native radiology practice
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HQ: San Francisco, CA, United States
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The Bloomberg of Loans
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HQ: San Francisco, CA, United States
What they do:
Hotels that run themselves
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HQ: San Francisco, CA, United States
What they do:
The AI Operating System for Auto Shops.
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HQ: San Francisco, CA, United States
What they do:
Training company-specific models that approve AI actions.
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HQ: San Francisco, CA, United States
What they do:
AI Brokers for Industrial Trade
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HQ: San Francisco, CA, United States