Top B2B Software Startups in San Francisco

Quick facts:

10 employeesYC S24Growth stage16 open roles

Cloud & infrastructure Applied AI & ML Data & analytics Developer tools

Thunder Compute

Hiring

What they do:

GPUs for Agents

Quick facts:

10 employeesYC S24Early stage3 open roles

Applied AI & ML Cloud & infrastructure

CTGT

Hiring

What they do:

The deterministic layer for frontier intelligence

Quick facts:

10 employeesYC F24Early stage3 open roles

Sim

Hiring

What they do:

Build autonomous AI agents for enterprise systems

Quick facts:

10 employeesYC X25Early stage5 open roles

Applied AI & ML AI agents & assistants

Bluejay

Hiring

What they do:

Test, monitor, and improve your voice and chat AI agents

Quick facts:

10 employeesYC X25Early stage

QualGent

Hiring

What they do:

AI Mobile App Quality Assurance Tester

Quick facts:

10 employeesYC X25Early stage

AI infrastructure & models Applied AI & ML Data & analytics

Besimple AI

Hiring

What they do:

Voice data for AI

Quick facts:

10 employeesYC X25Early stage

Applied AI & ML Legal, compliance & gov

Vesence

Hiring

What they do:

AI for High-Stakes Work

Quick facts:

10 employeesYC X25Early stage

Applied AI & ML Space, aviation & defense

Godela

Hiring

What they do:

AI Physics Engine to replace simulations and prototypes

Quick facts:

10 employeesYC X25Early stage

Developer tools Cloud & infrastructure

AgentMail

Hiring

What they do:

Email Inboxes for AI Agents

Quick facts:

10 employeesYC S25Early stage8 open roles

Wafer

What they do:

AI that makes AI fast

Quick facts:

15 employeesYC S25Growth stage

Applied AI & ML E-commerce & retail Social & community

Reacher

Hiring

What they do:

We automate creator marketing for the world's largest brands

Quick facts:

10 employeesYC S25Early stage8 open rolesRemote

Productivity & automation

Magnetic

Hiring

What they do:

AI Tax Preparer for CPA firms

Quick facts:

10 employeesYC S25Early stage

Legal, compliance & gov Applied AI & ML

Lexi

What they do:

AI Operating System for Legal Teams

Quick facts:

15 employeesYC F25Early stage

AI agents & assistants Applied AI & ML Travel & hospitality

Lance

Hiring

What they do:

AI Agents That Run Hotel Operations.

Quick facts:

10 employeesYC W26Early stage6 open roles

Meadow

What they do:

Point of Sale and Compliance SaaS for Cannabis Dispensaries

E-commerce & retail

Quick facts:

14 employeesYC W15Early stage

Productivity & automation Robotics & drones

Text Blaze

Hiring

What they do:

Slash commands anywhere

Quick facts:

9 employeesYC W21Early stageRemote

Varos

Hiring

What they do:

AI Business Analysts to gather requirements and optimize processes

Data & analytics

Quick facts:

9 employeesYC S21Early stage

Legal, compliance & gov Applied AI & ML Cloud & infrastructure

ROE

Hiring

What they do:

AI for risk and compliance

Quick facts:

9 employeesYC W24Early stage

Applied AI & ML Sales & marketing

Centralize

Hiring

What they do:

The relationship intelligence platform for enterprise revenue

Quick facts:

9 employeesYC W24Early stage

Applied AI & ML Cloud & infrastructure

Raindrop

Hiring

What they do:

Sentry for AI Agents

Quick facts:

9 employeesYC W24Growth stage9 open roles

Data & analytics Applied AI & ML Productivity & automation Sales & marketing

GetCrux

Hiring

What they do:

AI Creative Strategist

Quick facts:

9 employeesYC W24Early stage

HR & recruiting Applied AI & ML Productivity & automation Legal, compliance & gov

FirstWork

Hiring

What they do:

Rippling for seasonal workers

Quick facts:

9 employeesYC S24Growth stage10 open rolesRemote

Helium

Hiring

What they do:

Self Improving Software

Quick facts:

9 employeesYC S24Early stage

Applied AI & ML Legal, compliance & gov Banking & lending

Sphinx

What they do:

AI Compliance Analysts for Banks & Fintechs

Quick facts:

14 employeesYC F24Early stage

Sales & marketing Applied AI & ML

Ergo

Hiring

What they do:

Ergo is the context layer that helps revenue teams close more deals.

Quick facts:

9 employeesYC W25Early stage

Vector Legal

Hiring

What they do:

A premier AI-native law firm & legal operating system for Startups.

Legal, compliance & gov

Quick facts:

9 employeesYC W26Early stage

Applied AI & ML Developer tools Productivity & automation

Tara AI

What they do:

Meet Tara AI, your new engineering efficiency co-pilot.

Quick facts:

13 employeesYC W15Growth stageRemote

Medical devices & diagnostics

Rev Genomics

Hiring

What they do:

Rev is a biotechnology company creating better plants.

Quick facts:

8 employeesYC S17Growth stage

Developer tools Applied AI & ML Productivity & automation

WarpBuild

Hiring

What they do:

Accelerate software development with WarpBuild's 10x faster CI infra.

Quick facts:

8 employeesYC S21Early stageRemote

Sales & marketing Applied AI & ML

SilkChart

Hiring

What they do:

AI Sales Assistant to increase playbook adoption and win more deals

Quick facts:

8 employeesYC S22Early stageRemote

Applied AI & ML Mobility & automotive

ShortLoop

Hiring

What they do:

Phone AI that Captures Every Dealership Revenue Opportunity

Quick facts:

8 employeesYC W23Early stage

Applied AI & ML AI agents & assistants Sales & marketing

Berry

Hiring

What they do:

Scale customer success and onboarding with AI

Quick facts:

8 employeesYC W23Early stageRemote

Applied AI & ML Developer tools Manufacturing & chips

Silimate

Hiring

What they do:

Fast, efficient agents for chip design and debug

Quick facts:

8 employeesYC S23Early stage

Paradigm

Hiring

What they do:

A reimagined workspace with AI at its core

Quick facts:

8 employeesYC W24Early stage5 open roles

Applied AI & ML Social & community Media & entertainment

sync.

What they do:

AI lipsync tool for video content creators

Quick facts:

13 employeesYC W24Early stage