What they do:
AI Agents for Lending Operations
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HQ: San Francisco, CA, United States
Top B2B Software Startups in San Francisco
This list has 2,118 startups and was last updated on Oct 16, 2026. 572 of them are hiring right now. Largest teams: Stripe, Deel, and GrubMarket. Latest round: Jaccard raised $4.52M (Oct 15, 2026).
2,118 startupsPage 28 of 59
What they do:
The Lovable & Replit killers
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HQ: San Francisco, CA, United States
What they do:
Struct keeps prod running
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HQ: San Francisco, CA, United States
What they do:
The AI Assistant for Gmail
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HQ: San Francisco, CA, United States
What they do:
AI powered debugging notebooks for incident response
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HQ: San Francisco, CA, United States
What they do:
Building AI systems that improve from experience.
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HQ: San Francisco, CA, United States
What they do:
Hire amazing engineers by seeing how they use AI
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HQ: San Francisco, CA, United States
What they do:
A foundation model for physics.
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HQ: San Francisco, CA, United States
What they do:
Fast and Data-Driven Immigration Platform
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HQ: San Francisco, CA, United States
What they do:
Protect and Grow Long-tail Revenue
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HQ: San Francisco, CA, United States
What they do:
Test, monitor, and improve your voice agents
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HQ: San Francisco, CA, United States
What they do:
Continual Learning for Agents
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HQ: San Francisco, CA, United States
What they do:
Open Source React.js Library for AI Chat
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HQ: San Francisco, CA, United States
What they do:
Custom models trained on your data
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HQ: San Francisco, CA, United States
What they do:
Creator marketing that scales like paid ads
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HQ: San Francisco, CA, United States
What they do:
We automate your entire product development lifecycle.
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HQ: San Francisco, CA, United States
What they do:
Open-source frontier models for knowledge work
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HQ: San Francisco, CA, United States
What they do:
Understand your users beyond the numbers
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HQ: San Francisco, CA, United States
What they do:
A personal EA in your iMessage
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HQ: San Francisco, CA, United States
What they do:
Specialized AI for Critical Industries
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HQ: San Francisco, CA, United States
What they do:
Automatically write and update internal docs with every code commit.
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HQ: San Francisco, CA, United States
What they do:
Self-Driving CI: fast AI-native GitHub Actions runners
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HQ: San Francisco, CA, United States
What they do:
Build and ship native Swift apps with AI
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HQ: San Francisco, CA, United States
What they do:
Cursor for Email
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HQ: San Francisco, CA, United States
What they do:
Building medical school for AI Agents
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HQ: San Francisco, CA, United States
What they do:
AI content manager that grows your company's online presence
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HQ: San Francisco, CA, United States
What they do:
Truckload Planning at Machine Precision
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HQ: San Francisco, CA, United States
What they do:
AI employees trained on your firm's workflows.
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HQ: San Francisco, CA, United States
What they do:
Production infrastructure on autopilot
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HQ: San Francisco, CA, United States
What they do:
Digital transformation for real economy businesses
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HQ: San Francisco, CA, United States
What they do:
Studio-Grade Design at Scale
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HQ: San Francisco, CA, United States
What they do:
Continuous AI pentesting that finds and fixes vulnerabilities
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HQ: San Francisco, CA, United States
What they do:
AI clerks that automate your payables
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HQ: San Francisco, CA, United States
What they do:
Expressive conversational AI
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HQ: San Francisco, CA, United States
What they do:
Team chat to command all your company's coding agents
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HQ: San Francisco, CA, United States
What they do:
Insurance risk layer for physical AI
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HQ: San Francisco, CA, United States