What they do:
Your email assistant because you deserve a better morning
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HQ: San Francisco, CA, United States
Top B2B Software Startups in San Francisco
This list has 2,110 startups and was last updated on Oct 15, 2026. 572 of them are hiring right now. Largest teams: Stripe, Deel, and GrubMarket. Latest round: Modal raised $750M (Oct 14, 2026).
2,110 startupsPage 32 of 59
What they do:
The content engine that wins attention and drives growth.
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HQ: San Francisco, CA, United States
What they do:
Simple, LLM-first translation and internationalization for software
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HQ: San Francisco, CA, United States
What they do:
Making procurement easy
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HQ: San Francisco, CA, United States
What they do:
Generate a detailed log of everything you've worked on, automatically.
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HQ: San Francisco, CA, United States
What they do:
The open source Cursor alternative
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HQ: San Francisco, CA, United States
What they do:
Organizational productivity suite for companies
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HQ: San Francisco, CA, United States
What they do:
Turn the web into structured data
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HQ: San Francisco, CA, United States
What they do:
Compliance guardrails-as-a-service for AI applications
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HQ: San Francisco, CA, United States
What they do:
Automated physician scheduling
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HQ: San Francisco, CA, United States
What they do:
Voice + video AI interviewer
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HQ: San Francisco, CA, United States
What they do:
The best DOCX MCP for agents to edit microsoft word documents
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HQ: San Francisco, CA, United States
What they do:
AI agents to automate corporate transactions
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HQ: San Francisco, CA, United States
What they do:
Forward Deployed Research Services
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HQ: San Francisco, CA, United States
What they do:
The platform for automated hiring and workforce decisions.
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HQ: San Francisco, CA, United States
What they do:
Prompt and Context Optimization for Coding Agents
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HQ: San Francisco, CA, United States
What they do:
AI documentation engineer – test & autoimprove stale product docs
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HQ: San Francisco, CA, United States
What they do:
Environments for Long Horizon Work
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HQ: San Francisco, CA, United States
What they do:
We help companies win government funding with AI
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HQ: San Francisco, CA, United States
What they do:
Lovable for Chrome Plugins
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HQ: San Francisco, CA, United States
What they do:
The agentic AI Word editor
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HQ: San Francisco, CA, United States
What they do:
Zero code network tracer
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HQ: San Francisco, CA, United States
What they do:
AWS for AI Agents
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HQ: San Francisco, CA, United States
What they do:
The AI Maximalist Software Holding Company
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HQ: San Francisco, CA, United States
What they do:
Outbound Sequencing Infrastructure for Startups
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HQ: San Francisco, CA, United States
What they do:
The social network layer for AI apps
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HQ: San Francisco, CA, United States
What they do:
AI personal assistant for in-home sales
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HQ: San Francisco, CA, United States
What they do:
The health coach that texts you first
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HQ: San Francisco, CA, United States
What they do:
Build internal tools with AI
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HQ: San Francisco, CA, United States
What they do:
AI agents for conversational commerce
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HQ: San Francisco, CA, United States
What they do:
Headless Data Team
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HQ: San Francisco, CA, United States
What they do:
Foundational model research
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HQ: San Francisco, CA, United States
What they do:
AI Employees for Hotels
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HQ: San Francisco, CA, United States
What they do:
Building agents that reads logs and fixes issues on your behalf.
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HQ: San Francisco, CA, United States
What they do:
We turn traditional companies into AI companies
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HQ: San Francisco, CA, United States
What they do:
Embedded Sandboxes for Agents
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HQ: San Francisco, CA, United States