What they do:
Simpler and cheaper multi-cloud and cross-platform deployments.
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HQ: San Francisco, CA, United States
Top B2B Software Startups in San Francisco
This list has 2,110 startups and was last updated on Oct 15, 2026. 572 of them are hiring right now. Largest teams: Stripe, Deel, and GrubMarket. Latest round: Modal raised $750M (Oct 14, 2026).
2,110 startupsPage 31 of 59
What they do:
AI for humans
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HQ: San Francisco, CA, United States
What they do:
Observability and evaluation platform for LLM apps.
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HQ: San Francisco, CA, United States
What they do:
Automate your chargebacks with AI agents
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HQ: San Francisco, CA, United States
What they do:
orchestrate your coding agents with sudocode
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HQ: San Francisco, CA, United States
What they do:
The open source Postman alternative.
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HQ: San Francisco, CA, United States
What they do:
AI for legal & government
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HQ: San Francisco, CA, United States
What they do:
AI-native customer support platform
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HQ: San Francisco, CA, United States
What they do:
the AI coding app for thinking.
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HQ: San Francisco, CA, United States
What they do:
Voice Agents for Healthcare Operations
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HQ: San Francisco, CA, United States
What they do:
Helping Companies Deploy Email Agents in High Trust Domains
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HQ: San Francisco, CA, United States
What they do:
AI agents to enroll providers with payors
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HQ: San Francisco, CA, United States
What they do:
AI and Embeddings.
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HQ: San Francisco, CA, United States
What they do:
Modern patient engagement and remote therapeutic monitoring platform
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HQ: San Francisco, CA, United States
What they do:
Security for AI-native developers
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HQ: San Francisco, CA, United States
What they do:
AI agents for private market diligence, monitoring, and reporting
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HQ: San Francisco, CA, United States
What they do:
Describe It. Find It. Act On It.
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HQ: San Francisco, CA, United States
What they do:
AI agents for insurance claims
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HQ: San Francisco, CA, United States
What they do:
Speaking coach for non-native English professionals
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HQ: San Francisco, CA, United States
What they do:
AI media creation platform for creators and developers
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HQ: San Francisco, CA, United States
What they do:
Know what your customers want, because they told you.
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HQ: San Francisco, CA, United States
What they do:
A Unified Editor For AI Video
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HQ: San Francisco, CA, United States
What they do:
AI agent for construction drawings review
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HQ: San Francisco, CA, United States
What they do:
Win local search on ChatGPT & other LLMs
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HQ: San Francisco, CA, United States
What they do:
Effortless AI automation for business operations
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HQ: San Francisco, CA, United States
What they do:
Open source AI copilot that knows your company's code and its context
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HQ: San Francisco, CA, United States
What they do:
One living model of your software architecture
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HQ: San Francisco, CA, United States
What they do:
Transform your iMessage conversations into shareable stories
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HQ: San Francisco, CA, United States
What they do:
Open source agentic BI for founders
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HQ: San Francisco, CA, United States
What they do:
Providing quick product and design feedback via digital twins
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HQ: San Francisco, CA, United States
What they do:
Making everyone a software engineer
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HQ: San Francisco, CA, United States
What they do:
ai-native security engineering for mission critical codebases
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HQ: San Francisco, CA, United States
What they do:
New State of the Art for Browser Agents
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HQ: San Francisco, CA, United States
What they do:
Datadog for robots
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HQ: San Francisco, CA, United States
What they do:
API & SDK for RCS (the next-generation of texting)
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HQ: San Francisco, CA, United States
What they do:
Video editor built for AI
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HQ: San Francisco, CA, United States