What they do:
Open-source Agentic Development Environment
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HQ: San Francisco, CA, United States
Top B2B Software Startups in San Francisco
This list has 2,110 startups and was last updated on Oct 15, 2026. 572 of them are hiring right now. Largest teams: Stripe, Deel, and GrubMarket. Latest round: Modal raised $750M (Oct 14, 2026).
2,110 startupsPage 35 of 59
What they do:
Turn gatherings into lasting relationships.
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HQ: San Francisco, CA, United States
What they do:
API sandboxes, built for AI agents
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HQ: San Francisco, CA, United States
What they do:
The secure training data R&D engine for physical AI
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HQ: San Francisco, CA, United States
What they do:
Keeping contractors on the job site, not behind a desk.
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HQ: San Francisco, CA, United States
What they do:
Compression middleware that improves LLM outputs
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HQ: San Francisco, CA, United States
What they do:
Payments for Conversational Agents
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HQ: San Francisco, CA, United States
What they do:
API for performance-based payroll
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HQ: San Francisco, CA, United States
What they do:
Adversarial AI that breaks your AI
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HQ: San Francisco, CA, United States
What they do:
Using VLMs to Catch Damage
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HQ: San Francisco, CA, United States
What they do:
AI that runs factories.
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HQ: San Francisco, CA, United States
What they do:
The customer brain that connects data to explain customer behavior
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HQ: San Francisco, CA, United States
What they do:
FDE as a platform for rebuilding critical operations in software.
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HQ: San Francisco, CA, United States
What they do:
AI Cost Management: Track and attribute AI spend across every provider
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HQ: San Francisco, CA, United States
What they do:
AI Video Production for Professionals
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HQ: San Francisco, CA, United States
What they do:
AI coworker for video editors to ship more video faster
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HQ: San Francisco, CA, United States
What they do:
The Media Engine of the AI Era
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HQ: San Francisco, CA, United States
What they do:
We help software companies get discovered and used by AI agents
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HQ: San Francisco, CA, United States
What they do:
Turn how your team works into playbooks and agents
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HQ: San Francisco, CA, United States
What they do:
Make websites improve themselves.
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HQ: San Francisco, CA, United States
What they do:
Autonomous research agents for R&D and applied science
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HQ: San Francisco, CA, United States
What they do:
staffing firms with dreach grow revenue faster.
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HQ: San Francisco, CA, United States
What they do:
Near-real-time video infrastructure for LLMs
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HQ: San Francisco, CA, United States
What they do:
Company brain every AI-native enterprise runs on
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HQ: San Francisco, CA, United States
What they do:
Agentic operating system for auto repair shops
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HQ: San Francisco, CA, United States
What they do:
Control lab instruments with natural language.
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HQ: San Francisco, CA, United States
What they do:
Building AI Native Customs Brokerages
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HQ: San Francisco, CA, United States
What they do:
AI that turns your product into on-brand marketing content
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HQ: San Francisco, CA, United States
What they do:
Distributed runtime for AI workloads at scale
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HQ: San Francisco, CA, United States
What they do:
Staging Environments for Enterprise AI Agents
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HQ: San Francisco, CA, United States
What they do:
The control point for AI agents at work.
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HQ: San Francisco, CA, United States
What they do:
Security for agents that self-improves
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HQ: San Francisco, CA, United States
What they do:
AI Native Sourcing Broker For Overseas Manufacturing
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HQ: San Francisco, CA, United States
What they do:
The AI-native McKinsey
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HQ: San Francisco, CA, United States
What they do:
Automating open-ended research.
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HQ: San Francisco, CA, United States
What they do:
The AI revenue platform for D2C brands
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HQ: San Francisco, CA, United States