Zyper
Acquired
What they do:
Recreating social networks for brands.
Quick facts:
HQ: San Francisco, CA, United States
Top B2B Software Startups in San Francisco
This list has 2,110 startups and was last updated on Oct 15, 2026. 572 of them are hiring right now. Largest teams: Stripe, Deel, and GrubMarket. Latest round: Modal raised $750M (Oct 14, 2026).
2,110 startupsPage 45 of 59
Courier
Acquired
What they do:
The fastest way for developers to build notifications for their app.
Quick facts:
HQ: San Francisco, CA, United States
Command AI
Acquired
What they do:
AI-powered user assistance platform
Quick facts:
HQ: San Francisco, CA, United States
PlayAI
Acquired
What they do:
Our mission is to make Voice AI accessible and useful to all.
Quick facts:
HQ: San Francisco, CA, United States
YouTeam
Acquired
What they do:
We make it easy for startups to hire engineers.
Quick facts:
HQ: San Francisco, CA, United States
CrowdAI
Acquired
What they do:
CrowdAI is the world's leading no-code platform for vision AI
Quick facts:
HQ: San Francisco, CA, United States
Enzyme
Acquired
What they do:
Automating regulatory approval & compliance for life science companies
Quick facts:
HQ: San Francisco, CA, United States
Finley
Acquired
What they do:
Streamline your debt capital raise and management
Quick facts:
HQ: San Francisco, CA, United States
Tenjin
Acquired
What they do:
Mobile marketing analytics and infrastructure
Quick facts:
HQ: San Francisco, CA, United States
Guilded
Acquired
What they do:
Chat for gaming communities
Quick facts:
HQ: San Francisco, CA, United States
Arc
Acquired
What they do:
Banking & Funding for Startups
Quick facts:
HQ: San Francisco, CA, United States
TigerEye
Acquired
What they do:
AI for Construction
Quick facts:
HQ: San Francisco, CA, United States
Plato
Acquired
What they do:
Plato is the mentorship platform for engineering leaders
Quick facts:
HQ: San Francisco, CA, United States
Semantics3
Acquired
What they do:
Data and AI platform for Ecommerce & Cross-Border Logistics
Quick facts:
HQ: San Francisco, CA, United States
SigOpt
Acquired
What they do:
SigOpt is an Optimization-as-a-Service platform that seamlessly tunes…
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HQ: San Francisco, CA, United States
Truva
Acquired
What they do:
Sell more. Grind less with AI agents.
Quick facts:
HQ: San Francisco, CA, United States
Uiflow
Acquired
What they do:
No-code platform for enterprise software companies
Quick facts:
HQ: San Francisco, CA, United States
SketchDeck
Acquired
What they do:
Operating system for creative agencies
Quick facts:
HQ: San Francisco, CA, United States
Clara Labs
Acquired
What they do:
Clara is a human-in-the-loop assistant that helps automate repetitive…
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HQ: San Francisco, CA, United States
Searchlight
Acquired
What they do:
Talent AI improving quality of hire
Quick facts:
HQ: San Francisco, CA, United States
Breadcrumbs.io
Acquired
What they do:
No-code scoring engine identifying your most engaged upsell opps
Quick facts:
HQ: San Francisco, CA, United States
Onyx
Acquired
What they do:
Open Source AI Chat
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HQ: San Francisco, CA, United States
Requestly
Acquired
What they do:
Open-Source Postman alternative
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HQ: San Francisco, CA, United States
Smarking
Acquired
What they do:
Digitize $655B parking industry
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HQ: San Francisco, CA, United States
NexTravel
Acquired
What they do:
NexTravel is a centralized travel booking platform that helps…
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HQ: San Francisco, CA, United States
Askdata
Acquired
What they do:
Frictionless Data
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HQ: San Francisco, CA, United States
Beeper
Acquired
What they do:
One chat app to rule them all
Quick facts:
HQ: San Francisco, CA, United States
MyVR
Acquired
What they do:
The open platform for the vacation rental industry.
Quick facts:
HQ: San Francisco, CA, United States
ZumoDrive
Acquired
What they do:
Media in the cloud
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HQ: San Francisco, CA, United States
OmniVirt
Acquired
What they do:
OmniVirt is the leading VR Advertising platform for brands and…
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HQ: San Francisco, CA, United States
Tenant Turner
Acquired
What they do:
We help residential property managers eliminate vacancy.
Quick facts:
HQ: San Francisco, CA, United States
Hingeto
Acquired
What they do:
A B2B marketplace that connects inventory to online stores
Quick facts:
HQ: San Francisco, CA, United States
Lawyaw
Acquired
What they do:
Automating document-based workflows
Quick facts:
HQ: San Francisco, CA, United States
PopSQL
Acquired
What they do:
SQL editor for teams
Quick facts:
HQ: San Francisco, CA, United States
Central
Acquired
What they do:
Payroll, benefits, state compliance & other bullsh*t for startups
Quick facts:
HQ: San Francisco, CA, United States
Sepal AI
Acquired
What they do:
Data Development for Advanced AI
Quick facts:
HQ: San Francisco, CA, United States