Humanloop
Acquired
What they do:
Humanloop is the LLM evals platform for enterprises.
Quick facts:
HQ: San Francisco, CA, United States
Top B2B Software Startups in San Francisco
This list has 2,110 startups and was last updated on Oct 15, 2026. 572 of them are hiring right now. Largest teams: Stripe, Deel, and GrubMarket. Latest round: Modal raised $750M (Oct 14, 2026).
2,110 startupsPage 46 of 59
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Acquired
What they do:
Digital Sales Rooms (Acquired by MindTickle)
Quick facts:
HQ: San Francisco, CA, United States
Chargehound
Acquired
What they do:
Automate your chargeback dispute process. (Acquired by PayPal)
Quick facts:
HQ: San Francisco, CA, United States
Bun
Acquired
What they do:
Bun is an incredibly fast all-in-one JavaScript toolkit
Quick facts:
HQ: San Francisco, CA, United States
Metis
Acquired
What they do:
Infrastructure to build reliable agents
Quick facts:
HQ: San Francisco, CA, United States
DeepSource
Acquired
What they do:
Unified DevSecOps platform, helping developers ship good code.
Quick facts:
HQ: San Francisco, CA, United States
Aquarium Learning
Acquired
What they do:
We help ML teams improve their models by improving their datasets
Quick facts:
HQ: San Francisco, CA, United States
Tola
Acquired
What they do:
The simple, fast and free tool for businesses to pay and get paid
Quick facts:
HQ: San Francisco, CA, United States
Blaxel
Acquired
What they do:
The infrastructure for autonomous agents
Quick facts:
HQ: San Francisco, CA, United States
Chute
Acquired
What they do:
Discover the photos and videos people are taking of your brand or…
Quick facts:
HQ: San Francisco, CA, United States
Pagelever
Acquired
What they do:
Facebook analytics. Acquired by Unified in January 2013.
Quick facts:
HQ: San Francisco, CA, United States
Perfect Audience
Acquired
What they do:
Self-service display advertising for SaaS and online retail.
Quick facts:
HQ: San Francisco, CA, United States
Parse
Acquired
What they do:
Parse is the easiest way to build apps.
Quick facts:
HQ: San Francisco, CA, United States
Zencoder
Acquired
What they do:
Video Encoding API, Open source video player (video.js)
Quick facts:
HQ: San Francisco, CA, United States
RethinkDB
Acquired
What they do:
The open source database for the realtime web.
Quick facts:
HQ: San Francisco, CA, United States
Heyzap
Acquired
What they do:
Heyzap (acquired by Fyber for $45m in 2016) is one of the largest…
Quick facts:
HQ: San Francisco, CA, United States
Cloudkick
Acquired
What they do:
Cloudkick is system to manage cloud servers, such as the Rackspace Cloud and Amazon's EC2. Cloudkick provides an easy to use monitoring/alerting solution to…
Quick facts:
HQ: San Francisco, CA, United States
280 North
Acquired
What they do:
280 North is a web application company based on their proprietary application framework, Cappuccino. Along with Objective-J, Cappuccino provides a complete…
Quick facts:
HQ: San Francisco, CA, United States
Disqus
Acquired
What they do:
Add comments to your website.
Quick facts:
HQ: San Francisco, CA, United States
Xobni
Acquired
What they do:
Xobni makes your inbox and address book smarter. Xobni, and its Smartr product suite, discover all the people you've ever emailed, called or SMS'd, and…
Quick facts:
HQ: San Francisco, CA, United States
Clickfacts
Acquired
What they do:
ClickFacts is a Malware Software Solutions company for buyers and sellers of online media. Its automated plug and play malware discovery solution tests online…
Quick facts:
HQ: San Francisco, CA, United States
Natero
Acquired
What they do:
Data-driven customer success platform for B2B SaaS.
Quick facts:
HQ: San Francisco, CA, United States
Mattermark
Acquired
What they do:
Big Data Meets Startup Investing The best tool for tracking and…
Quick facts:
HQ: San Francisco, CA, United States
Hackermeter
Acquired
What they do:
Replacing resume screening with code challenges.
Quick facts:
HQ: San Francisco, CA, United States
Boostable
Acquired
What they do:
Advertising platform tools for marketplace sellers.
Quick facts:
HQ: San Francisco, CA, United States
Two Tap
Acquired
What they do:
Two Tap connects retailers to companies that want to sell their…
Quick facts:
HQ: San Francisco, CA, United States
Kuna Systems
Acquired
What they do:
We're making a smart, front door camera with intercom that lets you…
Quick facts:
HQ: San Francisco, CA, United States
Motionlead
Acquired
What they do:
Animated mobile ads.
Quick facts:
HQ: San Francisco, CA, United States
Liftigniter
Acquired
What they do:
Machine Learning personalization for dynamic digital properties -…
Quick facts:
HQ: San Francisco, CA, United States
Rickshaw
Acquired
What they do:
Same day local delivery, via API. Currently operating in SF.
Quick facts:
HQ: San Francisco, CA, United States
Wit.ai
Acquired
What they do:
Natural Language for Developers --Wit is an API that makes it easy…
Quick facts:
HQ: San Francisco, CA, United States
Avametric
Acquired
What they do:
Simulate clothes on your body.
Quick facts:
HQ: San Francisco, CA, United States
Replenish
Acquired
What they do:
Keurig machine for smoothies.
Quick facts:
HQ: San Francisco, CA, United States
Final
Acquired
What they do:
A credit card that drastically reduces payment fraud and gives…
Quick facts:
HQ: San Francisco, CA, United States
Smyte
Acquired
What they do:
Smyte stops bad actors on social networks and marketplaces.
Quick facts:
HQ: San Francisco, CA, United States
Nova
Acquired
What they do:
Nova puts the power of AI to work for you, enabling a more continuous…
Quick facts:
HQ: San Francisco, CA, United States