What they do:
Founder-level assistance whenever customers need it, at scale
Quick facts:
HQ: San Francisco, CA, United States
Top B2B Software Startups in the United States
This list has 3,865 startups and was last updated on Oct 15, 2026. 827 of them are hiring right now. Biggest hubs: San Francisco (2,110), New York (555), and Los Angeles (79). Largest teams: Stripe, Deel, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
3,865 startupsPage 31 of 108
BlueHill Payments
Hiring
What they do:
Client management, communication, and projects in one platform.
Quick facts:
HQ: Chicago, IL, United States
What they do:
Automate support ops natively in Slack
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HQ: New York, NY, United States
What they do:
Accelerate clinical trials with real-time, actionable insights
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HQ: San Francisco, CA, United States
What they do:
Webflow for the Backend
Quick facts:
HQ: New York, NY, United States
Finta
Hiring
What they do:
Magically simplify accounting and taxes
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Manage a swarm of AI agents to get real work done
Quick facts:
HQ: San Francisco, CA, United States
Inlet
Hiring
What they do:
AI timekeeping for legal professionals.
Quick facts:
HQ: New York, NY, United States
Ellipsis
Hiring
What they do:
Cloud platform for coding agents
Quick facts:
HQ: New York, NY, United States
What they do:
AI-enabled procurement for government
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HQ: New York, NY, United States
What they do:
Give Your Employee An Employee
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HQ: San Francisco, CA, United States
Deep24
Hiring
What they do:
AI coach for your entire life
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The orchestration platform for teams who ship.
Quick facts:
HQ: New York, NY, United States
Roger
Hiring
What they do:
Roger is an AI SDR that automates outbound sales and follows up 24/7.
Quick facts:
HQ: Austin, TX, United States
What they do:
AI Supply Chain Manager for CPG
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HQ: San Francisco, CA, United States
What they do:
The user infrastructure platform
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HQ: San Francisco, CA, United States
RetroFix
Hiring
What they do:
Automate any workflow using plain english
Quick facts:
HQ: New York, NY, United States
What they do:
An AI physics simulator for AI chip design
Quick facts:
HQ: San Francisco, CA, United States
Substrate
Hiring
What they do:
Artificial Intelligence for your medical billing team
Quick facts:
HQ: San Francisco, CA, United States
Mage Legal
Hiring
What they do:
Automatic AI Legal Diligence
Quick facts:
HQ: San Francisco, CA, United States
Zettascale Computing
Hiring
What they do:
Chips for frontier AI
Quick facts:
HQ: San Francisco, CA, United States
Cerulion
Hiring
What they do:
Open source operating system for robots
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HQ: San Francisco, CA, United States
Sonatoria
Hiring
What they do:
Helping Startups Grow Organically
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HQ: Los Angeles, CA, United States
What they do:
Collaborative workspace for patent litigators
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HQ: San Francisco, CA, United States
Rescript
Hiring
What they do:
AI for Legal & Public Policy Teams
Quick facts:
HQ: Washington, DC, United States
What they do:
The Localization Engineering Platform
Quick facts:
HQ: San Francisco, CA, United States
HumanLayer
Hiring
What they do:
The multiplayer control plane for your software factory
Quick facts:
HQ: San Francisco, CA, United States
Paragon
Hiring
What they do:
The AI Growth Engine for Industrials
Quick facts:
HQ: San Francisco, CA, United States
Atlog
Hiring
What they do:
Outbound voice and text AI without a prompt
Quick facts:
HQ: New York, NY, United States
Thirdlayer
Hiring
What they do:
Continual learning for enterprise AI
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HQ: San Francisco, CA, United States
What they do:
Specialized AI for Every Job
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HQ: San Francisco, CA, United States
Alkali
Hiring
What they do:
The smarter way to estimate steel.
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HQ: Houston, TX, United States
Synthetic Society
Hiring
What they do:
Synthetic Videos to Simulate Real Users
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HQ: New York, NY, United States
MangoDesk
Hiring
What they do:
Long-horizon RL environments
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Create Whiteboard Explainer Videos with AI from a Prompt or Document
Quick facts:
HQ: Stockton, CA, United States
Orange Slice
Hiring
What they do:
Agentic sales enrichment spreadsheet
Quick facts:
HQ: San Francisco, CA, United States