What they do:
Simulate your customers with AI agents
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HQ: Boston, MA, United States
Top B2B Software Startups in the United States
This list has 3,865 startups and was last updated on Oct 15, 2026. 827 of them are hiring right now. Biggest hubs: San Francisco (2,110), New York (555), and Los Angeles (79). Largest teams: Stripe, Deel, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
3,865 startupsPage 37 of 108
What they do:
AI Infra for real-time vision applications
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HQ: San Francisco, CA, United States
VOYGR
Hiring
What they do:
Real-world place intelligence for AI apps and agents
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HQ: San Francisco, CA, United States
YC W26Early stage
Cardinal
Hiring
What they do:
Revenue Agents for GTM teams
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HQ: San Francisco, CA, United States
YC W26Early stage
What they do:
Agents that run short-term rental operations end-to-end
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HQ: San Francisco, CA, United States
What they do:
Real-world sandboxes to test and train AI agents
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HQ: San Francisco, CA, United States
What they do:
Live Evaluation Arenas for Financial Work
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HQ: New York, NY, United States
AgentPhone
Hiring
What they do:
Phone Numbers for AI Agents
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HQ: San Francisco, CA, United States
YC X26Early stage
What they do:
Find and engage with desperate buyers across LinkedIn, Email, and X
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HQ: San Francisco, CA, United States
What they do:
Scale AI scientists whose own breakthroughs accelerate the next.
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HQ: San Francisco, CA, United States
What they do:
Automated LiveOps for Game Studios
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HQ: San Francisco, CA, United States
What they do:
Autonomous Customer Operations
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HQ: San Francisco, CA, United States
What they do:
The AI-native trading company: factory prices, delivered, one number
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HQ: San Francisco, CA, United States
What they do:
The AI BPO for financial servies, run by computer-use agents
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HQ: San Francisco, CA, United States
What they do:
Earned intelligence for every company
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HQ: San Francisco, CA, United States
What they do:
Supply chain compliance and cost savings
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HQ: Salt Lake City, UT, United States
What they do:
AI that finds value creation opportunities across enterprise…
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HQ: San Francisco, CA, United States
Operon
Hiring
What they do:
Agentic data layer for manufacturing & process industries.
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HQ: San Francisco, CA, United States
YC S26Early stage
Lamb Labs
Hiring
What they do:
Lightning fast chips with hardcoded AI models
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Grok bot for GTM & Revenue teams
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HQ: San Francisco, CA, United States
What they do:
Agents that run middle/back-office operations for Private Capital
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HQ: New York, NY, United States
What they do:
Context layer for enterprise AI surveying employees with voice agents
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HQ: San Francisco, CA, United States
What they do:
We tell sellers exactly when a company is ready to buy.
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HQ: San Francisco, CA, United States
Spine
Hiring
What they do:
We run benefits, payroll & compliance for startups, for free
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HQ: San Francisco, CA, United States
YC F26Early stage
What they do:
A live watermark inside AI voice that survives phone calls
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HQ: San Francisco, CA, United States
What they do:
One-click screen sharing with installation-free viewing on all devices
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HQ: San Francisco, CA, United States
What they do:
WorkFlowy is a better way to manage information. It provides a simple…
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HQ: New York, NY, United States
What they do:
Sourcing marketplace for semiconductor fab spare parts.
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HQ: Newport Beach, CA, United States
What they do:
Full-service web, mobile, & cloud studio providing professional…
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HQ: Austin, TX, United States
What they do:
Your AI-powered creative apprentice 🪄
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HQ: New York, NY, United States
What they do:
Better, faster tech vendor research
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HQ: Los Angeles, CA, United States
What they do:
AI-Native Restaurant POS
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HQ: San Francisco, CA, United States
What they do:
Sell beyond the store.
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HQ: San Francisco, CA, United States
What they do:
The Best Way to Sign Contracts Since Handshakes. Roger that.
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HQ: New York, NY, United States
What they do:
LinkedIn content consultancy and scheduling platform for busy founders
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HQ: San Diego, CA, United States
What they do:
Mobile app and coaching program that helps employees sleep better
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HQ: San Francisco, CA, United States