What they do:
Predict how market participants behave
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HQ: San Francisco, CA, United States
Top B2B Software Startups in the United States
This list has 3,865 startups and was last updated on Oct 15, 2026. 827 of them are hiring right now. Biggest hubs: San Francisco (2,110), New York (555), and Los Angeles (79). Largest teams: Stripe, Deel, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
3,865 startupsPage 54 of 108
What they do:
Industrial Controllers built for AI
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HQ: Los Angeles, CA, United States
What they do:
AI native platform for real estate closings
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HQ: San Francisco, CA, United States
What they do:
Derivatives Exchange for Compute
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HQ: New York, NY, United States
What they do:
We find where AI agents fail, then train better models to run them.
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HQ: San Francisco, CA, United States
What they do:
The AI-native radiology practice
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HQ: San Francisco, CA, United States
What they do:
The Bloomberg of Loans
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HQ: San Francisco, CA, United States
What they do:
Hotels that run themselves
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HQ: San Francisco, CA, United States
What they do:
The AI Operating System for Auto Shops.
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HQ: San Francisco, CA, United States
What they do:
Training company-specific models that approve AI actions.
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HQ: San Francisco, CA, United States
What they do:
AI Brokers for Industrial Trade
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HQ: San Francisco, CA, United States
What they do:
Helping startups win gov contracts
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HQ: San Francisco, CA, United States
What they do:
AI agents for compliance at institutional trading firms
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HQ: San Francisco, CA, United States
What they do:
Multiplayer workspace for agents and humans
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HQ: San Francisco, CA, United States
What they do:
Distributed, hardware-agnostic AI inference
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HQ: San Francisco, CA, United States
What they do:
Self-optimizing inference cloud for faster, cheaper AI
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HQ: San Francisco, CA, United States
What they do:
Autonomous rovers to make the ‘Google Maps’ of underground utilities
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HQ: San Francisco, CA, United States
What they do:
AI tools for the chips your AI runs on
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HQ: San Francisco, CA, United States
What they do:
Next-generation agent operating system
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HQ: San Francisco, CA, United States
What they do:
The biggest crowdsourced benchmark for Computer-Use
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HQ: San Francisco, CA, United States
What they do:
AI that works for in-house legal teams
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HQ: San Francisco, CA, United States
What they do:
Open source AI gateway that turns your traffic into better models
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HQ: San Francisco, CA, United States
What they do:
Test agents in realistic worlds built from production usage
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HQ: San Francisco, CA, United States
What they do:
On-device AI that knows your entire life and does your work overnight.
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HQ: San Francisco, CA, United States
What they do:
AI users that test your app on every device and browser
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HQ: San Francisco, CA, United States
What they do:
World's Earliest Test for Alzheimer's Biomarkers
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HQ: San Francisco, CA, United States
What they do:
Lakehouse-as-a-Service (LaaS)
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HQ: San Francisco, CA, United States
What they do:
Agents running industrial enterprises from back office to shop floor
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HQ: San Francisco, CA, United States
What they do:
AI for the industries that power America.
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HQ: San Francisco, CA, United States
What they do:
Turning infrastructure demand into action
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HQ: San Francisco, CA, United States
What they do:
Intelligent Cloud for AI workloads
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HQ: San Francisco, CA, United States
What they do:
Give AI agents the right context at the right moment
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HQ: San Francisco, CA, United States
What they do:
Automate on-call at agent-scale.
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HQ: San Francisco, CA, United States
What they do:
Building in-house, frontier AI labs for companies
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HQ: San Francisco, CA, United States
What they do:
The AI desktop.
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HQ: San Francisco, CA, United States
What they do:
Fast inference for voice
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HQ: San Francisco, CA, United States