What they do:
Building programmable therapeutics for the immune system
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HQ: San Francisco, CA, United States
Top Biotech Startups in San Francisco
This list has 134 startups and was last updated on Oct 15, 2026. 21 of them are hiring right now. Largest teams: Benchling, BillionToOne, and Ansa Biotechnologies. Latest round: Altay Therapeutics raised $15.7M (Oct 2, 2026).
134 startupsPage 2 of 4
b12 Labs
Hiring
What they do:
Making hard molecules for Pharma and Biotech
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HQ: San Francisco, CA, United States
Exonic
Hiring
What they do:
Exonic is an AI-native cell and gene therapeutics company.
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HQ: San Francisco, CA, United States
Neuromorphic
Hiring
What they do:
Building robots to automate wetlabs
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HQ: San Francisco, CA, United States
What they do:
Programmable biology company for psychoactive effect design
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HQ: San Francisco, CA, United States
What they do:
Using protein coupling to build new therapies
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HQ: San Francisco, CA, United States
What they do:
Accelerate clinical trials with real-time, actionable insights
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HQ: San Francisco, CA, United States
What they do:
We sequence your gut and build the probiotics it’s missing
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HQ: San Francisco, CA, United States
What they do:
We stop cows from burping methane.
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HQ: San Francisco, CA, United States
What they do:
Elevated mRNA for transformative medicines.
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HQ: San Francisco, CA, United States
What they do:
RNA intelligence for precision medicine
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HQ: San Francisco, CA, United States
What they do:
A research lab for one
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HQ: San Francisco, CA, United States
What they do:
Enabling T cell immunotherapy discovery, development and manufacturing
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HQ: San Francisco, CA, United States
What they do:
Elevating mental health to be a part of your daily coffee ritual.
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HQ: San Francisco, CA, United States
What they do:
Genetic Medicine with Small Molecules
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HQ: San Francisco, CA, United States
What they do:
Your biopharma team, from molecule design to portfolio strategy
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HQ: San Francisco, CA, United States
What they do:
Breakthrough medicines unlocking the biology of heme
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HQ: San Francisco, CA, United States
What they do:
Gen AI molecular simulations that reproduce wetlab results
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HQ: San Francisco, CA, United States
What they do:
Full Stack Pharmaceutical Company for Personalized Peptides and GLP-1s
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HQ: San Francisco, CA, United States
What they do:
Synvivia applies chemical control over cell behavior
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HQ: San Francisco, CA, United States
What they do:
Our tests help eradicate cancer by telling doctors whether they got…
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HQ: San Francisco, CA, United States
What they do:
Smart gels for local drug delivery to the gut
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HQ: San Francisco, CA, United States
What they do:
Shiru leverages ML to create proteins to feed the world sustainably.
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HQ: San Francisco, CA, United States
What they do:
We make bacteria and plants that clean up pollution.
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HQ: San Francisco, CA, United States
What they do:
Activating an overlooked force in medicine - the patient.
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HQ: San Francisco, CA, United States
What they do:
Automating Data Entry for Clinical Trials
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HQ: San Francisco, CA, United States
What they do:
Enzyme design models.
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HQ: San Francisco, CA, United States
What they do:
The world's first AI-maximalist pharma company
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HQ: San Francisco, CA, United States
What they do:
A Foundation Model for Microbial Communities.
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HQ: San Francisco, CA, United States
What they do:
Evolutionary intelligence for autoimmune disease
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HQ: San Francisco, CA, United States
What they do:
YourChoice therapeutics is revolutionizing the contraceptive market…
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HQ: San Francisco, CA, United States
What they do:
We build better immunotherapies
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HQ: San Francisco, CA, United States
What they do:
Growing micro-organs to find new drugs
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HQ: San Francisco, CA, United States
What they do:
Engineering microbes for miners to unlock billions in trapped metal
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HQ: San Francisco, CA, United States
What they do:
24/7 Personal Health & Longevity Companion
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HQ: San Francisco, CA, United States
What they do:
Extrapolative AI to unlock First-in-Class drugs
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HQ: San Francisco, CA, United States