What they do:
Run AI pipelines 10x faster
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HQ: New York, NY, United States
Top Cloud Infrastructure Startups in the United States
This list has 388 startups and was last updated on Oct 15, 2026. 107 of them are hiring right now. Biggest hubs: San Francisco (302), New York (44), and Los Angeles (8). Largest teams: Fivetran, PagerDuty, and Firebase. Latest round: Supabase raised $150M (Oct 2, 2026).
388 startupsPage 7 of 11
What they do:
Test, evaluate & observe your LLM applications
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HQ: New York, NY, United States
What they do:
Open source tools for developing generative AI applications
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HQ: New York, NY, United States
What they do:
Agents that handle security work
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HQ: New York, NY, United States
What they do:
Simpler and cheaper multi-cloud and cross-platform deployments.
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HQ: San Francisco, CA, United States
What they do:
Helping Companies Deploy Email Agents in High Trust Domains
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HQ: San Francisco, CA, United States
What they do:
Prompt and Context Optimization for Coding Agents
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HQ: San Francisco, CA, United States
What they do:
AWS for AI Agents
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HQ: San Francisco, CA, United States
What they do:
Building agents that reads logs and fixes issues on your behalf.
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HQ: San Francisco, CA, United States
What they do:
Embedded Sandboxes for Agents
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HQ: San Francisco, CA, United States
What they do:
Reinforcement learning as a service
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HQ: San Francisco, CA, United States
What they do:
Abundant Intelligence for Everyone
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HQ: San Francisco, CA, United States
What they do:
Robots for the inspection and maintenance of data centers
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HQ: Boston, MA, United States
What they do:
AI Takeoffs for Electrical
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HQ: New York, NY, United States
What they do:
Sandboxes for AI agents
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HQ: San Francisco, CA, United States
What they do:
Independent AI evaluations lab
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HQ: New York, NY, United States
What they do:
Run open models as fast as your hardware allows
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HQ: San Francisco, CA, United States
What they do:
The continuous oversight engine for clinical trials
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HQ: San Francisco, CA, United States
What they do:
Building intellectually curious AI
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HQ: San Francisco, CA, United States
What they do:
Everything on anyone.
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HQ: San Francisco, CA, United States
What they do:
Find what's losing you customers and money in your AI agent and fix it
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Platform Engineering
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HQ: San Francisco, CA, United States
What they do:
Self-tuning search for products and files
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HQ: San Francisco, CA, United States
What they do:
Infra to build your own software factory
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HQ: New York, NY, United States
What they do:
AI SRE agent that triages, coordinates, and fixes production incidents
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HQ: San Francisco, CA, United States
What they do:
Infrastructure for Autonomous Science
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HQ: San Francisco, CA, United States
What they do:
API sandboxes, built for AI agents
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HQ: San Francisco, CA, United States
What they do:
Compression middleware that improves LLM outputs
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HQ: San Francisco, CA, United States
What they do:
Payments for Conversational Agents
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HQ: San Francisco, CA, United States
What they do:
AI that runs factories.
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HQ: San Francisco, CA, United States
What they do:
iMessage infrastructure for business
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HQ: New York, NY, United States
What they do:
staffing firms with dreach grow revenue faster.
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HQ: San Francisco, CA, United States
What they do:
Near-real-time video infrastructure for LLMs
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HQ: San Francisco, CA, United States
What they do:
Distributed runtime for AI workloads at scale
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HQ: San Francisco, CA, United States
What they do:
The control point for AI agents at work.
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HQ: San Francisco, CA, United States
What they do:
The IDE for Tokenmaxxers
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HQ: Boston, MA, United States