What they do:
Protocol Labs makes internet protocols: IPFS, Filecoin, and more.
Quick facts:
HQ: San Francisco, CA, United States
Top Crypto & Web3 Startups in San Francisco
This list has 33 startups and was last updated on Oct 15, 2026. 5 of them are hiring right now. Largest teams: Protocol Labs, Quantstamp, and CoinTracker.
33 startups
What they do:
Security auditing for Web3
Quick facts:
HQ: San Francisco, CA, United States
CoinTracker
Hiring
What they do:
The gold standard in cryptocurrency portfolio tracking and taxes
Quick facts:
HQ: San Francisco, CA, United States
Hapi
Hiring
What they do:
Stocks and cryptos trading app with zero commissions and no minimums…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Global neobank for emerging markets
Quick facts:
HQ: San Francisco, CA, United States
OWNY
Hiring
What they do:
AI driven payment rails for emerging market banks.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Stablecoin API for global payments
Quick facts:
HQ: San Francisco, CA, United States
Conviction
Hiring
What they do:
Anyone Can Trade
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Mobile marketplace for trading used goods.
Quick facts:
HQ: San Francisco, CA, United States
LootRush
Hiring
What they do:
The global operating account you truly deserve.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Trade with superhuman instinct
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The Face Filter NFT Marketplace
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The world's simplest Bitcoin self-custody solution
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The social trading app for stocks, memes, and perps
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The smarter way to manage USD earnings globally
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Stablecoin Global Bank Account
Quick facts:
HQ: San Francisco, CA, United States
Dharma Labs
Acquired
What they do:
The easiest way to buy 74k+ crypto tokens with USD
Quick facts:
HQ: San Francisco, CA, United States
Cypher
Acquired
What they do:
Crypto Neo-Bank (WhatsApp moment for bank accounts)
Quick facts:
HQ: San Francisco, CA, United States
TaoFi
Acquired
What they do:
The financial layer for decentralized AI
Quick facts:
HQ: San Francisco, CA, United States
Satsuma
Acquired
What they do:
Reliable blockchain indexing & querying for web3 engineering teams.
Quick facts:
HQ: San Francisco, CA, United States
Winter
Acquired
What they do:
Credit card checkout for NFTs
Quick facts:
HQ: San Francisco, CA, United States
Surematics
Acquired
What they do:
We help commercial insurance brokers structure complicated…
Quick facts:
HQ: San Francisco, CA, United States
SimpleHash
Acquired
What they do:
Multi-chain token data platform
Quick facts:
HQ: San Francisco, CA, United States
YC W22Early stage
Abundance Labs
Shut down
What they do:
Abundance Labs incubates and builds alternative currency marketplace…
Quick facts:
HQ: San Francisco, CA, United States
Hedgehog
Shut down
What they do:
Cryptocurrency Robo-adviser. Buy. Balance. Relax.
Quick facts:
HQ: San Francisco, CA, United States
Sonar
Shut down
What they do:
Minecraft meets Discord
Quick facts:
HQ: San Francisco, CA, United States
Bifrost
Shut down
What they do:
Wills and Estate Management for Crypto
Quick facts:
HQ: San Francisco, CA, United States
SlashAuth
Shut down
What they do:
The solution for fine-grained access control in web3
Quick facts:
HQ: San Francisco, CA, United States
Cashmere
Shut down
What they do:
Crypto wallet for web3 startups
Quick facts:
HQ: San Francisco, CA, United States
Notebook Labs
Shut down
What they do:
Decentralized, anonymous, and accountable identity on Web3.
Quick facts:
HQ: San Francisco, CA, United States
Serica
Shut down
What they do:
Financial payment and loan services for the Medical Cannabis and…
Quick facts:
HQ: San Francisco, CA, United States
Peg (formerly Paymobil)
Shut down
What they do:
The super simple stablecoin wallet with free transactions
Quick facts:
HQ: San Francisco, CA, United States
Canopi
Shut down
What they do:
API to measure and eliminate carbon emissions
Quick facts:
HQ: San Francisco, CA, United States
Questions and answers
How many startups are on this list?
There are 33 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
5 of them are hiring right now, including CoinTracker, Hapi, and OWNY.
Which of them have the largest teams?
By team size: Protocol Labs (130 employees), Quantstamp (80 employees), and CoinTracker (70 employees).