
Coinbase
What they do:
Buy, sell, and manage cryptocurrencies.
Quick facts:
HQ: Los Angeles, CA, United States
This list has 71 startups and was last updated on Oct 15, 2026. 13 of them are hiring right now. Biggest hubs: San Francisco (33), New York (19), and Los Angeles (6). Largest teams: Coinbase, Protocol Labs, and Quicknode.

What they do:
Buy, sell, and manage cryptocurrencies.
Quick facts:
HQ: Los Angeles, CA, United States

What they do:
Protocol Labs makes internet protocols: IPFS, Filecoin, and more.
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HQ: San Francisco, CA, United States

What they do:
Tools & infra to build and scale high-quality blockchain applications.
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HQ: Miami, FL, United States

What they do:
Security auditing for Web3
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HQ: San Francisco, CA, United States
What they do:
The gold standard in cryptocurrency portfolio tracking and taxes
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HQ: San Francisco, CA, United States

What they do:
This isn't just a marketplace; we're shaping the future of digital…
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HQ: New York, NY, United States

What they do:
Banking, corporate cards, stablecoin payments – available globally.
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HQ: Minneapolis, MN, United States

What they do:
Crypto-currency trading platform.
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HQ: Los Angeles, CA, United States

What they do:
The Notabene platform is the trust layer for global money movement.
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HQ: New York, NY, United States

What they do:
Your global dollar account powered by stablecoins
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HQ: New York, NY, United States

What they do:
Stocks and cryptos trading app with zero commissions and no minimums…
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HQ: San Francisco, CA, United States

What they do:
SpruceID lets users control their data across the web.
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HQ: New York, NY, United States

What they do:
Global neobank for emerging markets
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HQ: San Francisco, CA, United States

What they do:
Open-source, design centric software for interacting with blockchains
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HQ: New York, NY, United States

What they do:
AI driven payment rails for emerging market banks.
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HQ: San Francisco, CA, United States

What they do:
AI-Native Finance OS
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HQ: New York, NY, United States

What they do:
The Trading Terminal For Crypto Traders
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HQ: Austin, TX, United States

What they do:
A social streaming platform powered by creators and fans
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HQ: Los Angeles, CA, United States

What they do:
Stackup helps businesses manage their crypto assets.
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HQ: Los Angeles, CA, United States

What they do:
Stablecoin API for global payments
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HQ: San Francisco, CA, United States

What they do:
Accelerate verifiable computing
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HQ: Boston, MA, United States

What they do:
Trade memecoins
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HQ: New York, NY, United States

What they do:
Anyone Can Trade
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HQ: San Francisco, CA, United States

What they do:
Building the NASDAQ for Real Estate.
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HQ: Los Angeles, CA, United States

What they do:
Crypto On and Off Ramp for Latam
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HQ: Miami, FL, United States

What they do:
Trade memecoins, perpetuals, and earn yield.
Quick facts:
HQ: Austin, TX, United States

What they do:
Mobile marketplace for trading used goods.
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HQ: San Francisco, CA, United States

What they do:
The global operating account you truly deserve.
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HQ: San Francisco, CA, United States

What they do:
Account abstraction wallets as a service
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HQ: Los Angeles, CA, United States

What they do:
Trade with superhuman instinct
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HQ: San Francisco, CA, United States

What they do:
Automated sweep account, invest without the stress of speculating
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HQ: Salt Lake City, UT, United States

What they do:
Palantir for Web3
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HQ: New York, NY, United States

What they do:
The Face Filter NFT Marketplace
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HQ: San Francisco, CA, United States

What they do:
Zero-Knowledge security without seed phrases or backup codes
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HQ: Denver, CO, United States

What they do:
Spend crypto anywhere online
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HQ: Houston, TX, United States

What they do:
The world's simplest Bitcoin self-custody solution
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HQ: San Francisco, CA, United States
There are 71 startups on this list, last updated on Oct 15, 2026.
13 of them are hiring right now, including Quicknode, CoinTracker, and Slash.
By team size: Coinbase (6,112 employees), Protocol Labs (130 employees), and Quicknode (115 employees).
The biggest hubs are San Francisco (33), New York (19), and Los Angeles (6).