Quick facts:
HQ: Boulder, CO, United States
Incorporated: 2021
Funding:
$21M · Equity · Feb 2026
Top Deep Tech Startups in the United States
This list has 1,386 startups and was last updated on Oct 15, 2026. 306 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: DoorDash, EquipmentShare, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
1,386 startupsPage 25 of 39
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HQ: Bellville, TX, United States
Incorporated: 2024
Funding:
$20.4M · Equity · May 2026
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HQ: New York, NY, United States
Funding:
$20M · Equity · Mar 2026
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HQ: Palm Beach Gardens, FL, United States
Incorporated: 2025
Funding:
$20M · Equity · Feb 2026
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HQ: Buffalo, NY, United States
Funding:
$20M · Debt · Feb 2026
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HQ: Houston, TX, United States
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$18.6M · Equity · Sep 2026
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HQ: Columbus, OH, United States
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$18.3M · Equity · Feb 2026
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HQ: Solana Beach, CA, United States
Funding:
$18.1M · Equity · Oct 2026
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HQ: Raleigh, NC, United States
Incorporated: 2022
Funding:
$17.2M · Equity · Apr 2026
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HQ: Windermere, FL, United States
Incorporated: 2026
Funding:
$17M · Debt · Mar 2026
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HQ: Waltham, MA, United States
Funding:
$16.9M · Equity · Oct 2026
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HQ: San Jose, CA, United States
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$16.1M · Debt · Jan 2026
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HQ: Knoxville, TN, United States
Funding:
$16M · Equity · Jun 2026
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HQ: Waltham, MA, United States
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$15.5M · Equity · Oct 2026
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HQ: Hallandale, FL, United States
Incorporated: 2021
Funding:
$15M · Equity · Apr 2026
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HQ: Scotts Valley, CA, United States
Funding:
$15M · Equity · May 2026
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HQ: Tukwila, WA, United States
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$14.9M · Options · Jan 2026
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HQ: Cambridge, MA, United States
Incorporated: 2024
Funding:
$14.6M · Equity · Mar 2026
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HQ: Dover, DE, United States
Incorporated: 2024
Funding:
$11.8M · Equity · Apr 2026
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HQ: Tulsa, OK, United States
Funding:
$11.4M · Equity · Jan 2026
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HQ: Edmond, OK, United States
Incorporated: 2026
Funding:
$10.8M · Equity · Apr 2026
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HQ: Morrisville, NC, United States
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$10.8M · Equity · Jan 2026
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HQ: Hanover, MD, United States
Incorporated: 2023
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$10.5M · Equity · Mar 2026
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HQ: Ames, IA, United States
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$10.2M · Equity · Jun 2026
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HQ: Brooklyn, NY, United States
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$10.1M · Equity · Jan 2026
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HQ: Costa Mesa, CA, United States
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$10M · Equity · Apr 2026
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HQ: Euless, TX, United States
Incorporated: 2026
Funding:
$10M · Apr 2026
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HQ: Thornton, CO, United States
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$10M · Equity · Jan 2026
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HQ: Redwood City, CA, United States
Incorporated: 2024
Funding:
$9.94M · Equity · May 2026
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HQ: New York, NY, United States
Incorporated: 2025
Funding:
$9.85M · Equity · Feb 2026
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HQ: Lewes, DE, United States
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$9.45M · Equity · Mar 2026
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HQ: Dublin, CA, United States
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$9.35M · Equity · Mar 2026
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HQ: Lakewood, OH, United States
Incorporated: 2025
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$9.29M · Equity · Jan 2026
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HQ: Lewes, DE, United States
Incorporated: 2025
Funding:
$9.25M · Equity · Apr 2026
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HQ: Lathrop, CA, United States
Funding:
$9M · Equity · Mar 2026
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HQ: San Francisco, CA, United States
Incorporated: 2024
Funding:
$8.81M · Equity · Jan 2026