Almond
Shut down
What they do:
We make it easy to get great ObGyn care in-person and over telehealth
Quick facts:
HQ: Los Angeles, CA, United States
Top Digital Health Startups in California
This list has 210 startups and was last updated on Oct 15, 2026. 61 of them are hiring right now. Biggest hubs: San Francisco (190), Los Angeles (12), and San Diego (2). Largest teams: Truepill, Clipboard, and Athelas. Latest round: Malama Health raised $5.32M (Feb 26, 2026).
210 startupsPage 6 of 6
InnaMed
Shut down
What they do:
At-home blood testing: measure + analyze + enhance.
Quick facts:
HQ: San Francisco, CA, United States
Spect
Shut down
What they do:
Value-based retinal screening in primary care to prevent blindness.
Quick facts:
HQ: San Francisco, CA, United States
Northwind
Shut down
What they do:
Tele-dermatology for chronic skin conditions
Quick facts:
HQ: Los Angeles, CA, United States
CrowdMed
Shut down
What they do:
CrowdMed harnesses the wisdom of crowds to solve difficult medical…
Quick facts:
HQ: San Francisco, CA, United States
Lully
Shut down
What they do:
Lully is developing an under-the-mattress technology that precisely…
Quick facts:
HQ: San Francisco, CA, United States
Quadrant Eye
Shut down
What they do:
Breaking new ground in online eyecare.
Quick facts:
HQ: San Francisco, CA, United States
Remy
Shut down
What they do:
Making it simpler for medical clinics to work with insurance
Quick facts:
HQ: San Francisco, CA, United States
Comet Health
Shut down
What they do:
Digital platform for pelvic floor physical therapy
Quick facts:
HQ: San Francisco, CA, United States
Amulyte
Shut down
What they do:
Remote monitoring & activity tracking system for seniors.
Quick facts:
HQ: San Francisco, CA, United States
Butter Systems
Shut down
What they do:
Replacing the paper restaurant menu with an interactive experience at…
Quick facts:
HQ: San Francisco, CA, United States
Nightingale
Shut down
What they do:
App for managing care of autistic students
Quick facts:
HQ: San Francisco, CA, United States
Wink Health
Shut down
What they do:
The digital sleep clinic
Quick facts:
HQ: San Francisco, CA, United States
Stitch Health
Shut down
What they do:
Care Coordination Platform for Healthcare
Quick facts:
HQ: San Francisco, CA, United States
DoseDr
Shut down
What they do:
Helping diabetes patients use the correct amount of insulin,…
Quick facts:
HQ: San Francisco, CA, United States
Anchor Health
Shut down
What they do:
Modernizing home health care agencies with software, hardware, and…
Quick facts:
HQ: San Francisco, CA, United States
PhysioHealth
Shut down
What they do:
An enterprise health benefits platform that rewards employees for…
Quick facts:
HQ: San Francisco, CA, United States
RigPlenish
Shut down
What they do:
On average each Ambulance run is two hours long, 40 minutes is spent…
Quick facts:
HQ: San Francisco, CA, United States
Airo Health
Shut down
What they do:
Airo is an AI wearable to track mental health.
Quick facts:
HQ: San Francisco, CA, United States
Semantix
Shut down
What they do:
AI for medical billing
Quick facts:
HQ: San Francisco, CA, United States
Caelum Health
Shut down
What they do:
Caelum Health is replacing drugs with software. We use behavioral…
Quick facts:
HQ: San Francisco, CA, United States
RideAlong
Shut down
What they do:
We save lives by giving police and health workers key info to safely…
Quick facts:
HQ: San Francisco, CA, United States
Simple Strips
Shut down
What they do:
Low-cost blood glucose test strips scanned with a smartphone camera…
Quick facts:
HQ: San Francisco, CA, United States
Kips Health
Shut down
What they do:
The only patient engagement software that pays you.
Quick facts:
HQ: Los Angeles, CA, United States
RadMate AI
Shut down
What they do:
Copilot for radiologists
Quick facts:
HQ: San Francisco, CA, United States
Baseline AI
Shut down
What they do:
AI document creation and data management for clinical trials
Quick facts:
HQ: San Francisco, CA, United States
Ruta Health
Shut down
What they do:
Async personalized and actionable health education by real doctors
Quick facts:
HQ: San Francisco, CA, United States
CareLedger
Shut down
What they do:
CareLedger helps companies save money on healthcare expenses by…
Quick facts:
HQ: San Francisco, CA, United States
YC S15Early stage
Nutrigene
Shut down
What they do:
Personalized liquid supplements based your health data
Quick facts:
HQ: San Francisco, CA, United States
YC W18Early stage
DailyDoctor
Shut down
What they do:
Daily telehealth care for people with COPD, CHF, hypertension, and…
Quick facts:
HQ: San Francisco, CA, United States