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Top E-commerce Startups in the United States

This list has 279 startups and was last updated on Oct 15, 2026. 53 of them are hiring right now. Biggest hubs: San Francisco (142), New York (56), and Los Angeles (20). Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Astraea, Inc./DE raised $175K (Oct 14, 2026).

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Questions and answers

How many startups are on this list?

There are 279 startups on this list, last updated on Oct 15, 2026.

Which of them are hiring?

53 of them are hiring right now, including DoorDash, Instacart, and GOAT Group.

Which of them have the largest teams?

By team size: DoorDash (8,600 employees), GrubMarket (4,548 employees), and Instacart (3,000 employees).

Which of them raised money recently?

Latest rounds: Astraea, Inc./DE — $175K Equity (Oct 2026), Modal — $750M Series D (Oct 2026), and Santé — $15M (Oct 2026).

Where are they based?

The biggest hubs are San Francisco (142), New York (56), and Los Angeles (20).