What they do:
Extrapolative AI to unlock First-in-Class drugs
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HQ: San Francisco, CA, United States
Top Healthcare Startups in California
This list has 551 startups and was last updated on Oct 15, 2026. 112 of them are hiring right now. Biggest hubs: San Francisco (419), Los Angeles (22), and San Diego (20). Largest teams: Gusto, Truepill, and Clipboard. Latest round: Renue Life Sciences raised $250K (Oct 14, 2026).
551 startupsPage 8 of 16
What they do:
AI nutrition coach in your pocket
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HQ: San Francisco, CA, United States
What they do:
The agentic OS for medical labs
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HQ: San Francisco, CA, United States
What they do:
AI-native CRO for clinical trial operations
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HQ: San Francisco, CA, United States
What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
AI-Native FDA Regulatory Services
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HQ: San Francisco, CA, United States
What they do:
Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States
What they do:
Oura Ring for Skin
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HQ: San Francisco, CA, United States
What they do:
Embodied Scientific Intelligence
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HQ: San Francisco, CA, United States
What they do:
A tool for pharmacists to find funding for patients who are unable to…
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HQ: Milpitas, CA, United States
What they do:
Tradewind translates scientific insight into innovative ways of…
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HQ: San Francisco, CA, United States
What they do:
Synkrino's AI, SATIS is a powerful, unbiased discovery system for…
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HQ: San Francisco, CA, United States
What they do:
mRNA therapeutics to extend healthspan entering clinical trials
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HQ: San Francisco, CA, United States
What they do:
23andMe for environmental exposures
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HQ: San Francisco, CA, United States
What they do:
We are developing a drug to burn calories and increase metabolism…
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HQ: San Francisco, CA, United States
What they do:
Menten AI designs peptide and protein therapeutics using quantum…
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HQ: San Francisco, CA, United States
What they do:
Bioengineered kidneys for patients with kidney failure
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HQ: San Diego, CA, United States
What they do:
Neurostimulation implant to restore hearing & speech understanding
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HQ: San Francisco, CA, United States
What they do:
Reinventing respiration monitoring
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HQ: Los Angeles, CA, United States
What they do:
Targeting the Tumor Ecosystem to address cancer drug resistance.
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HQ: San Francisco, CA, United States
What they do:
Enabling Tissue Targeting of Therapies
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HQ: San Francisco, CA, United States
What they do:
High quality mRNA for therapeutic application
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HQ: San Diego, CA, United States
What they do:
AI Diagnosis of Heart Disease
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HQ: San Francisco, CA, United States
What they do:
AI assisted documentation for PT/OT/SLP
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HQ: San Francisco, CA, United States
What they do:
Single source of truth for your clinic's finances and supply chain.
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HQ: San Francisco, CA, United States
What they do:
Automating nutrition tracking.
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HQ: San Francisco, CA, United States
What they do:
Genetically engineering plants for disease resistance.
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HQ: San Francisco, CA, United States
What they do:
CRM Co-Pilot for Medtech Sales
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HQ: San Francisco, CA, United States
What they do:
ML to predict and prevent pregnancy complications
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HQ: San Diego, CA, United States
What they do:
AI relationship app that keeps couples together
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HQ: San Francisco, CA, United States
What they do:
Voice Agents for Healthcare Operations
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HQ: San Francisco, CA, United States
What they do:
Mobile app helping people better manage chronic health conditions
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HQ: San Francisco, CA, United States
What they do:
Modern patient engagement and remote therapeutic monitoring platform
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HQ: San Francisco, CA, United States
What they do:
AI physical therapy for athletes
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HQ: San Francisco, CA, United States
What they do:
AI front office assistant for physical therapy
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HQ: San Francisco, CA, United States
What they do:
Genetically engineered viruses that teach your immune system to kill…
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HQ: San Francisco, CA, United States