What they do:
Autonomous intake and RCM for specialty clinics.
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HQ: San Francisco, CA, United States
Top Healthcare Startups in California
This list has 551 startups and was last updated on Oct 15, 2026. 112 of them are hiring right now. Biggest hubs: San Francisco (419), Los Angeles (22), and San Diego (20). Largest teams: Gusto, Truepill, and Clipboard. Latest round: Renue Life Sciences raised $250K (Oct 14, 2026).
551 startupsPage 9 of 16
What they do:
A Disease Focused Biotech, Building Multiple Billion Dollar Drugs
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HQ: San Francisco, CA, United States
What they do:
Automated physician scheduling
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HQ: San Francisco, CA, United States
What they do:
Voice AI for medical language translation
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HQ: San Francisco, CA, United States
What they do:
The health coach that texts you first
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HQ: San Francisco, CA, United States
What they do:
AI agents for conversational commerce
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HQ: San Francisco, CA, United States
What they do:
RWE Generation in minutes
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HQ: San Francisco, CA, United States
What they do:
AI workers for Skilled Nursing and Senior Living Operations
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HQ: San Francisco, CA, United States
What they do:
Sandboxes for AI agents
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HQ: San Francisco, CA, United States
What they do:
The continuous oversight engine for clinical trials
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HQ: San Francisco, CA, United States
What they do:
Automating regulatory submissions for life sciences
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HQ: San Francisco, CA, United States
What they do:
The first Agentic platform for Oncology
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HQ: San Francisco, CA, United States
What they do:
Autonomous OS for healthcare
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HQ: San Francisco, CA, United States
What they do:
Multimodal foundation models to predict uncollected patient biology
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HQ: San Francisco, CA, United States
What they do:
AI Employees for Primary Care
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HQ: San Francisco, CA, United States
What they do:
Financial infrastructure for family caregiving
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HQ: San Francisco, CA, United States
What they do:
Control lab instruments with natural language.
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HQ: San Francisco, CA, United States
What they do:
The AI Workforce for Biopharma
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HQ: San Francisco, CA, United States
What they do:
AI-native patient engagement
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HQ: San Francisco, CA, United States
What they do:
We are a multi-strategy trading firm that trains AI traders.
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HQ: San Francisco, CA, United States
What they do:
Curing cancer. Starting with dogs.
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HQ: San Francisco, CA, United States
What they do:
The AI-native radiology practice
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HQ: San Francisco, CA, United States
What they do:
World's Earliest Test for Alzheimer's Biomarkers
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HQ: San Francisco, CA, United States
What they do:
Infra to make AI safe enough to practice medicine
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HQ: San Francisco, CA, United States
What they do:
Turns EHR data into study-ready datasets for hospital research teams
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HQ: San Francisco, CA, United States
What they do:
Your health plan should get better year-round. Not just once a year.
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HQ: San Francisco, CA, United States
What they do:
Perlara: building the YC for rare disease parents
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HQ: San Francisco, CA, United States
What they do:
Redefining the Standard of Care for Iron Deficiency Anemia
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Healthcare Intake
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HQ: San Francisco, CA, United States
What they do:
Empowering Physical Therapists to Go Independent
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HQ: San Francisco, CA, United States
What they do:
Monitoring and governance for deployed medical imaging AI
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HQ: San Francisco, CA, United States
What they do:
Vaccines for any cancer or infection in weeks.
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HQ: San Francisco, CA, United States
What they do:
Helps build social skills through daily practice
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HQ: San Francisco, CA, United States
What they do:
Customized fertility benefits for modern companies.
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HQ: San Francisco, CA, United States
YC S17Growth stage
What they do:
AI platform accelerating therapies for rare & inflammatory diseases.
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HQ: San Francisco, CA, United States
YC S19Early stage
What they do:
AI operating system for veterinary care
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HQ: San Francisco, CA, United States
YC W24Early stage