What they do:
We sequence your gut and build the probiotics it’s missing
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HQ: San Francisco, CA, United States
Top Startups in California
This list has 3,698 startups and was last updated on Oct 15, 2026. 827 of them are hiring right now. Biggest hubs: San Francisco (3,173), Los Angeles (197), and San Diego (39). Largest teams: DoorDash, Stripe, and Airbnb. Latest round: Renue Life Sciences raised $250K (Oct 14, 2026).
3,698 startupsPage 33 of 103
IMPACT Drones
Hiring
What they do:
Air Defense as a Service for Civilian Infrastructure.
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HQ: San Francisco, CA, United States
screenpipe
Hiring
What they do:
Turn your company's computer work into AI agents.
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HQ: San Francisco, CA, United States
What they do:
AI collections agency for late stage portfolios
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HQ: San Francisco, CA, United States
Aktoria Robotics
Hiring
What they do:
Human as API for robots
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HQ: San Francisco, CA, United States
Rational
Hiring
What they do:
First Zero-human Accounting Firm
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HQ: San Francisco, CA, United States
What they do:
Drone swarm defence at a small-unit level
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HQ: San Francisco, CA, United States
Edviro
Hiring
What they do:
AI That Operates Energy Infrastructure
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HQ: San Francisco, CA, United States
Rhem Labs
Hiring
What they do:
Home care technology for aging parents and their families
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HQ: San Francisco, CA, United States
Workers IO
Hiring
What they do:
Simulation Environments for Verifying Mission Critical Software
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HQ: San Francisco, CA, United States
Covera
Hiring
What they do:
AI-native OS for insurance brokers
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HQ: San Francisco, CA, United States
Vyra
Hiring
What they do:
Autonomous video editing for non-editors.
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HQ: San Francisco, CA, United States
What they do:
Mobile marketplace for trading used goods.
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HQ: San Francisco, CA, United States
What they do:
Quilt manages data like code so that companies can experiment faster
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HQ: San Francisco, CA, United States
What they do:
Catch student behavior problems before they start.
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HQ: San Francisco, CA, United States
What they do:
Vertically integrated commercial construction
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HQ: San Francisco, CA, United States
What they do:
Tesseract builds better thrusters for modern satellites
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HQ: Livermore, CA, United States
What they do:
We are using the gut microbiome to end cancer.
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HQ: San Diego, CA, United States
What they do:
Responsive materials, better lives.
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HQ: Los Angeles, CA, United States
What they do:
tEQuitable's mission is to create work culture that works for everyone
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HQ: San Francisco, CA, United States
What they do:
We turn CO2 into battery-grade graphite and oxygen.
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HQ: San Francisco, CA, United States
What they do:
AI Accounting for Founders & Accountants
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HQ: San Francisco, CA, United States
What they do:
Building Communities Through Play
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HQ: San Francisco, CA, United States
What they do:
The spot market for semiconductors
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HQ: San Francisco, CA, United States
What they do:
At-home oral health testing, coaching & care
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HQ: San Francisco, CA, United States
What they do:
World's fastest and most optimal route optimization engine
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HQ: Ontario, CA, United States
What they do:
Virtual Co-working Community
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HQ: San Francisco, CA, United States
What they do:
The personal coach and companion for cyclists.
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HQ: Truckee, CA, United States
What they do:
One tool to supercharge your productivity.
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HQ: San Francisco, CA, United States
What they do:
We stop cows from burping methane.
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HQ: San Francisco, CA, United States
What they do:
Customer support tool purpose-built for companies that sell APIs
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HQ: Truckee, CA, United States
Blink
Hiring
What they do:
Build fully functional apps with AI.
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HQ: San Francisco, CA, United States
What they do:
Agentic workflows for complex, long running business operations
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HQ: San Francisco, CA, United States
What they do:
No-Code LLM Application / Workflow Builder
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HQ: San Francisco, CA, United States
What they do:
Limitless Real Estate
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HQ: San Francisco, CA, United States
What they do:
Manufacturing more proteins with AI.
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HQ: San Francisco, CA, United States