
What they do:
AI-powered technology enabler and digital transformer of American…
Quick facts:
HQ: San Francisco, CA, United States
This list has 159 startups and was last updated on Oct 15, 2026. 38 of them are hiring right now. Biggest hubs: San Francisco (137) and Los Angeles (18). Largest teams: GrubMarket, Instacart, and Flexport. Latest round: Numerion Labs raised $19.8M (Mar 19, 2026).

What they do:
AI-powered technology enabler and digital transformer of American…
Quick facts:
HQ: San Francisco, CA, United States

What they do:
Marketplace for grocery delivery and pickup
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HQ: San Francisco, CA, United States

What they do:
Platform for global logistics.
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HQ: San Francisco, CA, United States

What they do:
We break viruses
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HQ: San Francisco, CA, United States

What they do:
Self-driving semi trucks.
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HQ: San Francisco, CA, United States

What they do:
The everything app for LATAM
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HQ: Los Angeles, CA, United States

What they do:
Artificial intelligence for drug discovery.
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HQ: San Francisco, CA, United States
Funding:
$19.8M · Equity · Mar 2026

What they do:
Construction & industrial logistics platform.
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HQ: Los Angeles, CA, United States

What they do:
Intelligence that runs your operations.
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HQ: San Francisco, CA, United States

What they do:
Modernizing global transportation payments.
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HQ: San Francisco, CA, United States

What they do:
BeGo Connects cargo shippers with truck suppliers in Mexico and US
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HQ: San Francisco, CA, United States

What they do:
We use human data and AI to develop better drugs faster.
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HQ: San Francisco, CA, United States

What they do:
The operating system powering ecommerce fulfillment
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HQ: Los Angeles, CA, United States

What they do:
Healthy packaged fresh food
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HQ: Los Angeles, CA, United States

What they do:
Nash is the digital logistics infrastructure for commerce
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HQ: San Francisco, CA, United States

What they do:
Automation platform for logistics
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HQ: San Francisco, CA, United States

What they do:
The automated solution for complex freight transactions.
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HQ: Los Angeles, CA, United States

What they do:
AI-Native Fresh Produce Logistics
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HQ: San Francisco, CA, United States

What they do:
Scheduling and workforce management SaaS for home healthcare providers
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HQ: Los Angeles, CA, United States

What they do:
Autonomous drones to help warehouses scan inventory.
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HQ: San Francisco, CA, United States

What they do:
Targeting Cancer with Click Chemistry
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HQ: San Francisco, CA, United States

What they do:
Using the immune system to cure disease
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HQ: San Francisco, CA, United States

What they do:
AI enabled marketplace matching trucks with jobs
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HQ: San Francisco, CA, United States

What they do:
The next generation of induced-proximity medicines.
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HQ: San Francisco, CA, United States

What they do:
AI workers for the logistics industry.
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HQ: San Francisco, CA, United States

What they do:
The operating system for shipping and receiving.
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HQ: San Francisco, CA, United States

What they do:
AI Agents for high-stakes work.
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HQ: San Francisco, CA, United States

What they do:
We create automation technology for the cannabis industry.
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HQ: Los Angeles, CA, United States

What they do:
An AI-powered supply chain compliance engine
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HQ: San Francisco, CA, United States

What they do:
Autonomous freight coordination
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HQ: San Francisco, CA, United States

What they do:
Book any load in 10 minutes
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HQ: San Francisco, CA, United States

What they do:
Route Optimisation platform for SMB in delivery & home services.
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HQ: San Francisco, CA, United States

What they do:
Using CRISPR to find treatments for cancer and inflammation
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HQ: San Francisco, CA, United States

What they do:
Generative AI for protein design
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HQ: San Francisco, CA, United States

What they do:
AI Broker for Tariff Refunds
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HQ: San Francisco, CA, United States

What they do:
Custom Parts, Manufactured in America 🇺🇸
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HQ: San Francisco, CA, United States
There are 159 startups on this list, last updated on Oct 15, 2026.
38 of them are hiring right now, including Instacart, Flexport, and Curri.
By team size: GrubMarket (4,548 employees), Instacart (3,000 employees), and Flexport (3,000 employees).
Latest rounds: Numerion Labs — $19.8M Equity (Mar 2026).
The biggest hubs are San Francisco (137) and Los Angeles (18).