What they do:
Scale AI scientists whose own breakthroughs accelerate the next.
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HQ: San Francisco, CA, United States
Top Startups in California
This list has 3,713 startups and was last updated on Oct 16, 2026. 826 of them are hiring right now. Biggest hubs: San Francisco (3,181), Los Angeles (198), and San Diego (40). Largest teams: DoorDash, Stripe, and Airbnb. Latest round: hiyo raised $20.8M (Oct 15, 2026).
3,713 startupsPage 38 of 104
What they do:
Automated LiveOps for Game Studios
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HQ: San Francisco, CA, United States
What they do:
Autonomous Customer Operations
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HQ: San Francisco, CA, United States
What they do:
The AI-native trading company: factory prices, delivered, one number
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HQ: San Francisco, CA, United States
What they do:
The AI BPO for financial servies, run by computer-use agents
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HQ: San Francisco, CA, United States
What they do:
Earned intelligence for every company
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HQ: San Francisco, CA, United States
What they do:
The company brain for construction companies
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HQ: San Francisco, CA, United States
What they do:
AI that finds value creation opportunities across enterprise…
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HQ: San Francisco, CA, United States
What they do:
The most capable American-made humanoid robot for $1,688
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HQ: San Francisco, CA, United States
What they do:
Full Stack Pharmaceutical Company for Personalized Peptides and GLP-1s
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HQ: San Francisco, CA, United States
Operon
Hiring
What they do:
Agentic data layer for manufacturing & process industries.
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HQ: San Francisco, CA, United States
YC S26Early stage
Lamb Labs
Hiring
What they do:
Lightning fast chips with hardcoded AI models
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Grok bot for GTM & Revenue teams
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HQ: San Francisco, CA, United States
What they do:
Real-time data warehouse for agents
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HQ: San Francisco, CA, United States
What they do:
Context layer from employee voices to improve & automate workflows
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HQ: San Francisco, CA, United States
What they do:
We tell sellers exactly when a company is ready to buy.
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HQ: San Francisco, CA, United States
Spine
Hiring
What they do:
We run benefits, payroll & compliance for startups, for free
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HQ: San Francisco, CA, United States
YC F26Early stage
What they do:
A live watermark inside AI voice that survives phone calls
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HQ: San Francisco, CA, United States
What they do:
One-click screen sharing with installation-free viewing on all devices
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HQ: San Francisco, CA, United States
What they do:
Sourcing marketplace for semiconductor fab spare parts.
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HQ: Newport Beach, CA, United States
What they do:
Synvivia applies chemical control over cell behavior
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HQ: San Francisco, CA, United States
What they do:
Nuvola is transforming battery manufacturing, making EV batteries…
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HQ: Los Angeles, CA, United States
What they do:
Our tests help eradicate cancer by telling doctors whether they got…
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HQ: San Francisco, CA, United States
What they do:
Smart gels for local drug delivery to the gut
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HQ: San Francisco, CA, United States
What they do:
Shiru leverages ML to create proteins to feed the world sustainably.
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HQ: San Francisco, CA, United States
What they do:
World's largest library of interactive lessons for kids
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HQ: San Francisco, CA, United States
What they do:
Better, faster tech vendor research
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HQ: Los Angeles, CA, United States
What they do:
AI-Native Restaurant POS
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HQ: San Francisco, CA, United States
What they do:
Sell beyond the store.
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HQ: San Francisco, CA, United States
What they do:
LinkedIn content consultancy and scheduling platform for busy founders
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HQ: San Diego, CA, United States
What they do:
Mobile app and coaching program that helps employees sleep better
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HQ: San Francisco, CA, United States
What they do:
We make bacteria and plants that clean up pollution.
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HQ: San Francisco, CA, United States
What they do:
Activating an overlooked force in medicine - the patient.
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HQ: San Francisco, CA, United States
What they do:
2 sided Marketplace for accelerating medical research
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HQ: San Francisco, CA, United States
What they do:
Developing milk-inspired therapeutics for infectious diseases
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HQ: Davis, CA, United States
What they do:
Classify Anything
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HQ: CA, United States