What they do:
The continuous oversight engine for clinical trials
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HQ: San Francisco, CA, United States
Top Startups in San Francisco
This list has 3,173 startups and was last updated on Oct 15, 2026. 784 of them are hiring right now. Largest teams: DoorDash, Stripe, and Airbnb. Latest round: Modal raised $750M (Oct 14, 2026).
3,173 startupsPage 48 of 89
What they do:
Building intellectually curious AI
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HQ: San Francisco, CA, United States
What they do:
Building tiny frontier AI models that run on edge devices
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HQ: San Francisco, CA, United States
What they do:
The boring stuff, handled. Everything else, supercharged.
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HQ: San Francisco, CA, United States
What they do:
The agentic debugger for AI systems
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HQ: San Francisco, CA, United States
What they do:
Everything on anyone.
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HQ: San Francisco, CA, United States
What they do:
AI-Native Data Center Engineering
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HQ: San Francisco, CA, United States
What they do:
The Cursor for Chip Design - Delivering Silicon-Ready Chip Designs…
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HQ: San Francisco, CA, United States
What they do:
Your personal AI Assistant
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HQ: San Francisco, CA, United States
What they do:
Turns products into CLIs and agents into customers
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HQ: San Francisco, CA, United States
What they do:
Waymo for excavators
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HQ: San Francisco, CA, United States
What they do:
Planet-scale people discovery.
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HQ: San Francisco, CA, United States
What they do:
AI-native ERP for manufacturers
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HQ: San Francisco, CA, United States
What they do:
Synthetic populations for decisions
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HQ: San Francisco, CA, United States
What they do:
Automating regulatory submissions for life sciences
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HQ: San Francisco, CA, United States
What they do:
Payment infrastructure for AI agents
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HQ: San Francisco, CA, United States
What they do:
Find what's losing you customers and money in your AI agent and fix it
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HQ: San Francisco, CA, United States
What they do:
The Routing Layer for AI Agents
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HQ: San Francisco, CA, United States
What they do:
TikTok for Sports Trading
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HQ: San Francisco, CA, United States
What they do:
Identify churn risk and stay close to users at scale
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HQ: San Francisco, CA, United States
What they do:
The OS for data quality across any stack
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HQ: San Francisco, CA, United States
What they do:
AI Tax prep and accounting software for CPA firms
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HQ: San Francisco, CA, United States
What they do:
Delivering AI-powered situational awareness in tactical environments.
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HQ: San Francisco, CA, United States
What they do:
The sensitive data redaction layer for AI
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Platform Engineering
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HQ: San Francisco, CA, United States
What they do:
The control plane for AI agents.
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HQ: San Francisco, CA, United States
What they do:
A proactive desktop copilot. Clippy, but actually good.
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HQ: San Francisco, CA, United States
What they do:
AI language buddy in the games kids love
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HQ: San Francisco, CA, United States
What they do:
Self-tuning search for products and files
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HQ: San Francisco, CA, United States
What they do:
The coding agent that actually collaborates with you
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HQ: San Francisco, CA, United States
What they do:
Institutional liquidity across prediction markets
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HQ: San Francisco, CA, United States
What they do:
Code and browse in the same place
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HQ: San Francisco, CA, United States
What they do:
The first platform where families can create AI cartoons in minutes
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HQ: San Francisco, CA, United States
What they do:
The first Agentic platform for Oncology
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HQ: San Francisco, CA, United States
What they do:
AI support done right
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HQ: San Francisco, CA, United States
What they do:
The Marketplace for Complex Hobbies
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HQ: San Francisco, CA, United States