What they do:
Automating nutrition tracking.
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HQ: San Francisco, CA, United States
Top Wellness Startups in California
This list has 131 startups and was last updated on Oct 15, 2026. 22 of them are hiring right now. Biggest hubs: San Francisco (121), Los Angeles (5), and San Diego (2). Largest teams: Truepill, Clipboard, and Tempo. Latest round: Malama Health raised $5.32M (Feb 26, 2026).
131 startupsPage 3 of 4
What they do:
ML to predict and prevent pregnancy complications
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HQ: San Diego, CA, United States
What they do:
AI relationship app that keeps couples together
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HQ: San Francisco, CA, United States
What they do:
Mobile app helping people better manage chronic health conditions
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HQ: San Francisco, CA, United States
What they do:
AI physical therapy for athletes
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HQ: San Francisco, CA, United States
What they do:
Genetically engineered viruses that teach your immune system to kill…
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HQ: San Francisco, CA, United States
What they do:
A Disease Focused Biotech, Building Multiple Billion Dollar Drugs
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HQ: San Francisco, CA, United States
What they do:
Voice AI for medical language translation
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HQ: San Francisco, CA, United States
What they do:
The health coach that texts you first
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HQ: San Francisco, CA, United States
What they do:
Financial infrastructure for family caregiving
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HQ: San Francisco, CA, United States
What they do:
World's Earliest Test for Alzheimer's Biomarkers
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HQ: San Francisco, CA, United States
What they do:
Helps build social skills through daily practice
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HQ: San Francisco, CA, United States
What they do:
AI operating system for veterinary care
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HQ: San Francisco, CA, United States
YC W24Early stage
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HQ: Newport Beach, CA, United States
Incorporated: 2025
Funding:
$1.76M · Equity · Feb 2026
Modern Fertility
Acquired
What they do:
At-home fertility test for women who aren't ready for kids right now…
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HQ: San Francisco, CA, United States
Truepill
Acquired
What they do:
API-connected healthcare infrastructure.
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HQ: San Francisco, CA, United States
Spire Health
Acquired
What they do:
Remote patient monitoring for lung disease patients.
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HQ: San Francisco, CA, United States
Weilos
Acquired
What they do:
Weight loss coaching.
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HQ: San Francisco, CA, United States
Women.com
Acquired
What they do:
Quora/Cosmo for women
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HQ: San Francisco, CA, United States
Clear Genetics
Acquired
What they do:
Clear Genetics is scaling delivery of Genomic services
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HQ: San Francisco, CA, United States
Dear Brightly
Acquired
What they do:
Dear Brightly makes personalized prescription skincare products,…
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HQ: San Francisco, CA, United States
Verano Health
Acquired
What they do:
Nonprofit telehealth coaches for underserved Americans on Medicaid
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HQ: San Francisco, CA, United States
Verse Therapy
Acquired
What they do:
Connecting All Ages with Speech Language Pathologists
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HQ: San Francisco, CA, United States
Unwind Me
Acquired
What they do:
Homejoy for massage
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HQ: San Francisco, CA, United States
Kip Health
Acquired
What they do:
Therapy the way it should be: high quality in-person therapy sessions…
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HQ: San Francisco, CA, United States
Sayana
Acquired
What they do:
Affordable mental self-care for all. Acquired by Headspace Health.
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HQ: San Francisco, CA, United States
Galen AI
Acquired
What they do:
Personal AI healthcare agent, powered by clinical and wearable data.
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HQ: San Francisco, CA, United States
L.
Acquired
What they do:
L. makes award-winning personal care products with organic materials.
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HQ: San Francisco, CA, United States
YC S15Early stage
VetPronto
Shut down
What they do:
On demand veterinary house calls.
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HQ: San Francisco, CA, United States
Almond
Shut down
What they do:
We make it easy to get great ObGyn care in-person and over telehealth
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HQ: Los Angeles, CA, United States
Spect
Shut down
What they do:
Value-based retinal screening in primary care to prevent blindness.
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HQ: San Francisco, CA, United States
Mighty Health
Shut down
What they do:
All-in-one health program helping seniors with their daily function
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HQ: San Francisco, CA, United States
Tingles
Shut down
What they do:
Find content that helps you relax and fall asleep.
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HQ: San Francisco, CA, United States
Northwind
Shut down
What they do:
Tele-dermatology for chronic skin conditions
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HQ: Los Angeles, CA, United States
CrowdMed
Shut down
What they do:
CrowdMed harnesses the wisdom of crowds to solve difficult medical…
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HQ: San Francisco, CA, United States
Lully
Shut down
What they do:
Lully is developing an under-the-mattress technology that precisely…
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HQ: San Francisco, CA, United States