Oway
Hiring
What they do:
Building the open operating system for the automated physical economy.
Quick facts:
HQ: San Francisco, CA, United States
Top AI & Data Startups in California
This list has 1,550 startups and was last updated on Oct 15, 2026. 481 of them are hiring right now. Biggest hubs: San Francisco (1,471), Los Angeles (51), and San Diego (5). Largest teams: Cruise, Relativity Space, and Fivetran. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
1,550 startupsPage 6 of 44
Revyl
Hiring
What they do:
The Mobile Development Platform
Quick facts:
HQ: San Francisco, CA, United States
Weave
Hiring
What they do:
AI to understand and then route engineering work
Quick facts:
HQ: San Francisco, CA, United States
OWNY
Hiring
What they do:
AI driven payment rails for emerging market banks.
Quick facts:
HQ: San Francisco, CA, United States
Activeloop
Hiring
What they do:
Database for AI
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HQ: San Francisco, CA, United States
What they do:
AI-generated personalized nutrition solutions, built for you daily.
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HQ: San Francisco, CA, United States
What they do:
Brain Longevity
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HQ: San Francisco, CA, United States
Hypotenuse AI
Hiring
What they do:
AI-native Operating System for Enterprise Ecommerce Companies
Quick facts:
HQ: San Francisco, CA, United States
arnata
Hiring
What they do:
AI workers for the logistics industry.
Quick facts:
HQ: San Francisco, CA, United States
Lamar Health
Hiring
What they do:
Take Care of Shitty Paperwork for Expensive Drugs
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Water risk mitigation for industrial sites
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HQ: San Francisco, CA, United States
Velt
Hiring
What they do:
SDK for adding an agent and human governance layer to your product
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Underwater robotic vehicles that collect battery metals responsibly
Quick facts:
HQ: Los Angeles, CA, United States
Conduit
Hiring
What they do:
The operating system for shipping and receiving.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI Powered All-In-One Payroll, HR + Recruiting
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HQ: San Francisco, CA, United States
Ubicloud
Hiring
What they do:
Open source alternative to AWS
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HQ: San Francisco, CA, United States
What they do:
AI Applied Research
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HQ: San Francisco, CA, United States
Wordware
Hiring
What they do:
AI agents you can rely on
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HQ: San Francisco, CA, United States
Anthrogen
Hiring
What they do:
We work on generalizable tools for the next era of biotech.
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HQ: San Francisco, CA, United States
Kastle
Hiring
What they do:
AI employee for consumer lending
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HQ: San Francisco, CA, United States
Usul
Hiring
What they do:
AI Platform for Winning Defense & Government Contracts
Quick facts:
HQ: San Francisco, CA, United States
Laminar
Hiring
What they do:
Enterprise systems delivery without the turbulence.
Quick facts:
HQ: San Francisco, CA, United States
Toothy AI
Hiring
What they do:
AI for insurance verification & billing at dental clinics
Quick facts:
HQ: San Francisco, CA, United States
SalesPatriot
Hiring
What they do:
Supply chain superintelligence for distribution and procurement
Quick facts:
HQ: San Francisco, CA, United States
Vela
Hiring
What they do:
AI Recruiting Coordinator for Executive Search
Quick facts:
HQ: San Francisco, CA, United States
Brighterway
Hiring
What they do:
Streamlining the medical record review process in workers comp
Quick facts:
HQ: San Francisco, CA, United States
Calltree
Hiring
What they do:
Enterprise-grade AI support reps for call centers
Quick facts:
HQ: San Francisco, CA, United States
Lapel
Hiring
What they do:
Infrastructure to power every customer interaction.
Quick facts:
HQ: San Francisco, CA, United States
Semble
Hiring
What they do:
Takeoffs, design, and field work. Powered by AI.
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HQ: San Francisco, CA, United States
Reform
Hiring
What they do:
AI Agents for high-stakes work.
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HQ: San Francisco, CA, United States
Leaping AI
Hiring
What they do:
AI voice and texting agents
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HQ: San Francisco, CA, United States
What they do:
Your voice. Your health. We care.
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HQ: San Francisco, CA, United States
Sorting Robotics
Hiring
What they do:
We create automation technology for the cannabis industry.
Quick facts:
HQ: Los Angeles, CA, United States
Epsilon3
Hiring
What they do:
AI-Powered ERP, MES, and Test Software for Complex Operations
Quick facts:
HQ: Los Angeles, CA, United States
Zensors
Hiring
What they do:
AI to understand and automates the physical world
Quick facts:
HQ: San Francisco, CA, United States
Telmai
Hiring
What they do:
Automated data observability and quality for Data Lake
Quick facts:
HQ: San Francisco, CA, United States