What they do:
AI for the physical world
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HQ: San Francisco, CA, United States
Top AI Startups in California
This list has 1,429 startups and was last updated on Oct 15, 2026. 461 of them are hiring right now. Biggest hubs: San Francisco (1,355), Los Angeles (47), and San Diego (4). Largest teams: Cruise, Relativity Space, and Athelas. Latest round: Agriculture Scout AI raised $425K (Oct 13, 2026).
1,429 startupsPage 23 of 40
What they do:
Truckload Planning at Machine Precision
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HQ: San Francisco, CA, United States
What they do:
AI-native real estate services firm
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HQ: Los Angeles, CA, United States
What they do:
AI employees trained on your firm's workflows.
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HQ: San Francisco, CA, United States
What they do:
Digital transformation for real economy businesses
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HQ: San Francisco, CA, United States
What they do:
TikTok for language learning
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HQ: San Francisco, CA, United States
What they do:
Continuous AI pentesting that finds and fixes vulnerabilities
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HQ: San Francisco, CA, United States
What they do:
AI clerks that automate your payables
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HQ: San Francisco, CA, United States
What they do:
Large-scale real-world robot & human data for embodied AI
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HQ: San Francisco, CA, United States
What they do:
Expressive conversational AI
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HQ: San Francisco, CA, United States
What they do:
Team chat to command all your company's coding agents
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HQ: San Francisco, CA, United States
What they do:
Insurance risk layer for physical AI
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HQ: San Francisco, CA, United States
What they do:
Underwrite borrowers around the world in minutes
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HQ: San Francisco, CA, United States
What they do:
AI production engineer for regulated industries
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HQ: San Francisco, CA, United States
What they do:
Work with agents that already know you
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HQ: San Francisco, CA, United States
What they do:
Evals, RL environments and training data for creative tasks
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HQ: San Francisco, CA, United States
What they do:
Intelligence for cultural institutions
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HQ: San Francisco, CA, United States
What they do:
Evals for humans
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HQ: San Francisco, CA, United States
What they do:
Your Capable Desktop AI Companion
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HQ: Irvine, CA, United States
What they do:
24/7 Personal Health & Longevity Companion
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HQ: San Francisco, CA, United States
What they do:
Platform + FDEs that rebuild enterprises agent-first
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HQ: San Francisco, CA, United States
What they do:
Marketplace for AI agents to hire humans.
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HQ: San Francisco, CA, United States
What they do:
Building the Data Infrastructure layer for Physical AI.
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HQ: San Francisco, CA, United States
What they do:
Extrapolative AI to unlock First-in-Class drugs
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HQ: San Francisco, CA, United States
What they do:
AI nutrition coach in your pocket
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HQ: San Francisco, CA, United States
What they do:
AI-native CRO for clinical trial operations
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HQ: San Francisco, CA, United States
What they do:
Patreon for AI Originals
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HQ: San Francisco, CA, United States
What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
A personal or team assistant that works while you sleep
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HQ: San Francisco, CA, United States
What they do:
agents for the rest of us
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HQ: San Francisco, CA, United States
What they do:
We help lawyers start and scale AI-native law firms.
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HQ: San Francisco, CA, United States
What they do:
Watch and create anime
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HQ: San Francisco, CA, United States
What they do:
The market behind AI hardware.
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HQ: San Francisco, CA, United States
What they do:
Building a neutral, sovereign alternative to Starlink
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HQ: San Francisco, CA, United States
What they do:
Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States
What they do:
Reliable and safe data engineering and data science agents
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HQ: San Francisco, CA, United States