Top AI Startups in San Francisco

4 employeesYC W24Early stage

Applied AI & ML Sales & marketing

Duckie

Hiring

What they do:

Build AI Support Agents in Minutes

Quick facts:

4 employeesYC W24Early stage

Newton

Hiring

What they do:

AI-powered phone platform for dentists

Quick facts:

4 employeesYC W24Early stage2 open roles

Sales & marketing Applied AI & ML Productivity & automation

JustAI

Hiring

What they do:

Agentic Marketing Platform

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4 employeesYC W24Early stage

Applied AI & ML Productivity & automation

Brainbase Labs

Hiring

What they do:

The AI Labor Company

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4 employeesYC W24Early stage

Applied AI & ML Media & entertainment Social & community

Treblo

Hiring

What they do:

Create hit songs with AI

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4 employeesYC W24Early stage

Applied AI & ML AI agents & assistants

Marr Labs

What they do:

AI-voice agents that are indistinguishable from humans.

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9 employeesYC W24Early stage

Applied AI & ML Developer tools Media & entertainment

Cloudglue

Hiring

What they do:

The video context layer for AI.

Quick facts:

4 employeesYC S24Early stage

Applied AI & ML Manufacturing & chips

Conductor Quantum

Hiring

What they do:

AI that operates quantum computers for scientific discovery

Quick facts:

4 employeesYC S24Early stage

Onlook

Hiring

What they do:

The Developer tool for Designers

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4 employeesYC W25Early stage

Sales & marketing Applied AI & ML

Openbenchmarks

Hiring

What they do:

We help humans & agents pick tools via Independent Benchmarks

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4 employeesYC F24Early stage

Freebuff

Hiring

What they do:

The free coding agent

Quick facts:

4 employeesYC F24Early stage

Sales & marketing Applied AI & ML

Unusual

Hiring

What they do:

Market to AI agents

Quick facts:

4 employeesYC F24Early stage10 open roles

Adam

Hiring

What they do:

AI Powered CAD

Quick facts:

4 employeesYC W25Early stage

Social & community Applied AI & ML

Text.ai

Hiring

What they do:

Alfi - your group chat with social skills to bring friends closer

Quick facts:

4 employeesYC X25Early stage

Theorem

Hiring

What they do:

Program verification so even your systems engineers can vibecode

Quick facts:

4 employeesYC X25Early stage

Developer tools Applied AI & ML Cloud & infrastructure

TraceRoot.AI

Hiring

What they do:

Open Source AI Agent Improvement Platform

Quick facts:

4 employeesYC S25Early stage

Applied AI & ML Robotics & drones Data & analytics Manufacturing & chips

DeepAware AI (Robotics Center of Silicon Valley)

Hiring

What they do:

Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF.

Quick facts:

4 employeesYC S25Early stage

Novaflow

Hiring

What they do:

The AI data analyst for biology labs

Quick facts:

4 employeesYC S25Early stage

Applied AI & ML Accounting & finance ops

ProcIndex

Hiring

What they do:

AI-powered accounting automation for construction and manufacturing

Quick facts:

4 employeesYC S25Early stage

Floot

Hiring

What they do:

The app platform inside Claude and ChatGPT.

Quick facts:

4 employeesYC S25Early stage

AI agents & assistants Applied AI & ML

Deeptrace

Hiring

What they do:

AI agents for on-call

Quick facts:

4 employeesYC F25Early stage

Applied AI & ML Robotics & drones Manufacturing & chips

Darwin

Hiring

What they do:

Robots to build civilization

Quick facts:

4 employeesYC F25Early stage

Applied AI & ML Accounting & finance ops

Zarna

Hiring

What they do:

AI Associates for Middle-Market Private Equity

Quick facts:

4 employeesYC F25Early stage

Drafted

What they do:

Design your home instantly with AI

Quick facts:

9 employeesYC X26Early stage

Superset

Hiring

What they do:

Building self-improving software

Quick facts:

4 employeesYC X26Early stage

Sales & marketing Applied AI & ML

COACH

Hiring

What they do:

The AI Coach for in person sales reps.

Quick facts:

4 employeesYC S26Early stage

Applied AI & ML Sales & marketing

Netomi

Hiring

What they do:

Self-Driving Customer Care

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3 employeesYC W16Early stage23 open roles

Applied AI & ML Medical devices & diagnostics Digital health & care

Darmiyan

What they do:

Early detection of Alzheimer's disease

Quick facts:

8 employeesYC S17Early stage

Applied AI & ML Digital health & care

Rejoy Health

What they do:

AI workers that book, scribe, code, interpret, and answer clinicians

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8 employeesYC W21Early stageRemote

Applied AI & ML Data & analytics Manufacturing & chips Mobility & automotive

Versable

Hiring

What they do:

AI powered product description enhancement for the auto parts industry

Quick facts:

3 employeesYC W22Early stageRemote

Applied AI & ML Developer tools Cloud & infrastructure

MSPilot

Hiring

What they do:

Turn AI adoption into a recurring revenue line.

Quick facts:

3 employeesYC F25Early stageRemote

Poly

Hiring

What they do:

Intelligent Personal Cloud Storage

Quick facts:

3 employeesYC S22Early stage

Applied AI & ML AI agents & assistants

Alphawatch AI

What they do:

Relationship Coverage for Deal Teams

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8 employeesYC W23Early stageRemote

Applied AI & ML Productivity & automation Wellness & mental health

Solum Health

Hiring

What they do:

AI Automation for Therapy Practices

Quick facts:

3 employeesYC S22Early stage

Developer tools Applied AI & ML

Firecrawl

Hiring

What they do:

Building the library for superintelligence.

Quick facts:

3 employeesYC S22Growth stage34 open roles