Top AI Startups in San Francisco

3 employeesYC S22Growth stage34 open roles

Scout

Hiring

What they do:

Scout is an AI news aggregator that turns your role, industry, and…

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3 employeesYC W23Early stage

HR & recruiting Applied AI & ML AI agents & assistants

Serra

What they do:

Your 24/7 AI Recruiter

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8 employeesYC S23Early stage

Digital health & care Applied AI & ML Payments Insurance

Quill Bills

Hiring

What they do:

AI-Powered Medical Billing

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3 employeesYC S23Early stage

Travel & hospitality Applied AI & ML

Roame

Hiring

What they do:

Flight search engine using credit card points and miles

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3 employeesYC S23Early stage

Applied AI & ML Media & entertainment

LemonSlice

What they do:

Give your voice agents a face

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8 employeesYC W24Early stage

Applied AI & ML Biotech & pharma Wellness & mental health E-commerce & retail

GloGlo

Hiring

What they do:

Curing and preventing type 1 diabetes

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3 employeesYC W24Early stage

Applied AI & ML Real estate & construction

Feldy

What they do:

Field-First AI for home services

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8 employeesYC W24Early stageRemote

AI agents & assistants Applied AI & ML

Reprompt

Hiring

What they do:

AI Agents for Location

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3 employeesYC W24Early stage

Applied AI & ML Productivity & automation Developer tools

Party

What they do:

Secure multiplayer workspace for teams building with agents

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8 employeesYC S24Early stage

Travel & hospitality Applied AI & ML

Stardrift

Hiring

What they do:

AI travel planner

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3 employeesYC S24Early stage

Applied AI & ML Accounting & finance ops

Fazeshift

What they do:

AI agent for Accounts Receivable

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8 employeesYC S24Growth stage

Developer tools Applied AI & ML

cmux

Hiring

What they do:

Open source applied AI lab building next-gen devtools

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3 employeesYC S24Early stage

Hestus, Inc.

Hiring

What they do:

An AI-powered CAD software

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3 employeesYC S24Early stage

AI agents & assistants Applied AI & ML E-commerce & retail

Refactor

Hiring

What they do:

Deploying secure and reliable AI agents across healthcare, retail,…

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3 employeesYC S24Early stage

Applied AI & ML Investing & wealth

attimet

Hiring

What they do:

Building the Prime Radiant

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3 employeesYC F24Early stage

Legal, compliance & gov Applied AI & ML Sales & marketing

Luthor

Hiring

What they do:

Real-time governance for enterprise communications

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3 employeesYC F24Early stage

Real estate & construction Applied AI & ML

ArchiLabs

Hiring

What they do:

AI Data Center Design

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3 employeesYC F24Early stage

Applied AI & ML Developer tools

a0.dev

Hiring

What they do:

We make mobile apps using AI.

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3 employeesYC W25Early stage

Applied AI & ML Sales & marketing

10x

Hiring

What they do:

AI Sales Teams for Dental Practices

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3 employeesYC W25Early stage

Cybersecurity Applied AI & ML

Candor

Hiring

What they do:

Protect your data and stop insider risk

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3 employeesYC W25Early stage

Applied AI & ML Accounting & finance ops

Mesh

Hiring

What they do:

Eliminating accrual spreadsheets for faster month-end

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3 employeesYC W25Early stage17 open roles

Applied AI & ML AI agents & assistants

Rebolt

Hiring

What they do:

AI-Powered Company OS

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3 employeesYC W25Early stage

Dalus

Hiring

What they do:

AI-Powered Hardware System Design Software

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3 employeesYC W25Early stage

Vybe

What they do:

Secure internal apps. Built by AI in seconds. Powered by your data.

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8 employeesYC X25Early stage

Applied AI & ML Developer tools

Cactus Compute

What they do:

Automation Foundation Models For Tiny Devices

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8 employeesYC S25Early stage

Applied AI & ML Legal, compliance & gov

Code Four

Hiring

What they do:

Modernizing the police workflow.

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3 employeesYC X25Early stage

Productivity & automation AI agents & assistants Applied AI & ML

Bond

Hiring

What they do:

Your AI Chief of Staff

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3 employeesYC X25Early stage

Fifth Door

Hiring

What they do:

Create and play games with AI

Gaming Applied AI & ML

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3 employeesYC F25Early stage

Legal, compliance & gov Applied AI & ML

EffiGov

Hiring

What they do:

The AI OS for Cities

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3 employeesYC S25Early stage

Crypto & web3 Applied AI & ML Investing & wealth

Conviction

Hiring

What they do:

Anyone Can Trade

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3 employeesYC S25Early stage

Biotech & pharma Applied AI & ML Robotics & drones Logistics & supply chain

b12 Labs

Hiring

What they do:

Making hard molecules for Pharma and Biotech

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3 employeesYC S25Early stage4 open roles

Applied AI & ML Developer tools

Nozomio

Hiring

What they do:

product lab. focused on personal ai and context.

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3 employeesYC S25Early stage

Applied AI & ML Food & agriculture

Certus AI

What they do:

Replacing the restaurant phone line with Voice AI

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8 employeesYC S25Early stage

Logistics & supply chain Applied AI & ML Food & agriculture

burnt

Hiring

What they do:

Agentic Operating System for Food Supply Chain

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3 employeesYC S25Early stage

AI agents & assistants Applied AI & ML

Uplift AI

Hiring

What they do:

Foundational Voice Models for regional languages

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3 employeesYC S25Early stage