Prescience, Inc.
Hiring
What they do:
Superintelligent health insurance that keeps employees healthy
Quick facts:
HQ: San Francisco, CA, United States
Top B2B Software Startups in California
This list has 2,362 startups and was last updated on Oct 16, 2026. 592 of them are hiring right now. Biggest hubs: San Francisco (2,118), Los Angeles (80), and San Diego (13). Largest teams: Stripe, Deel, and GrubMarket. Latest round: Exploration Technologies, Inc./DE raised $8.3M (Oct 15, 2026).
2,362 startupsPage 17 of 66
RunAnywhere
Hiring
What they do:
Fastest inference anywhere: open models on-prem, hosted or on-device
Quick facts:
HQ: San Francisco, CA, United States
10x Science
Hiring
What they do:
The AI-native platform for next-generation protein characterization.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The AI-native observability platform for fast-moving engineering teams
Quick facts:
HQ: San Francisco, CA, United States
Interfaze
Hiring
What they do:
AI model built for high accuracy deterministic tasks
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Scale marketing campaigns across hundreds of personas
Quick facts:
HQ: San Francisco, CA, United States
LemonLime
Hiring
What they do:
Fully automated GTM for small business
Quick facts:
HQ: San Francisco, CA, United States
Pluto
Hiring
What they do:
LinkedIn for agents
Quick facts:
HQ: San Francisco, CA, United States
Ooak Data
Hiring
What they do:
We turn company data into training data
Quick facts:
HQ: San Francisco, CA, United States
TryNearby
Hiring
What they do:
Local creators for local businesses
Quick facts:
HQ: Los Angeles, CA, United States
Luca IQ
Hiring
What they do:
API-first tax engine for CPA firms and developers
Quick facts:
HQ: San Francisco, CA, United States
Runtime.si
Hiring
What they do:
Evaluation Infrastructure for Robotics (YC F26)
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Apozy makes every website safe to browse
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Opentable for the world's top restaurants; we help them increase…
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HQ: San Francisco, CA, United States
What they do:
AI Agent for Home Design
Quick facts:
HQ: Los Angeles, CA, United States
Safepay
Hiring
What they do:
Digital payments for businesses in Pakistan
Quick facts:
HQ: San Francisco, CA, United States
Hyperbrowser
Hiring
What they do:
Web infra for AI agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
A single point integration for secure and automated EV charging.
Quick facts:
HQ: San Francisco, CA, United States
Stackup
Hiring
What they do:
Stackup helps businesses manage their crypto assets.
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
The largest freight scheduling network in the industry.
Quick facts:
HQ: San Francisco, CA, United States
Zudo
Hiring
What they do:
AI Workers for Extended Service Contracts
Quick facts:
HQ: San Francisco, CA, United States
Pier
Hiring
What they do:
Stripe for Credit - Trusted Credit Compliance Partner
Quick facts:
HQ: San Francisco, CA, United States
Kino AI
Hiring
What they do:
Kino is an AI media manager and video editor for humans and agents.
Quick facts:
HQ: San Francisco, CA, United States
Health Harbor
Hiring
What they do:
Using generative AI to call insurance for healthcare clinics
Quick facts:
HQ: San Francisco, CA, United States
Metalware
Hiring
What they do:
Firmware cybersecurity
Quick facts:
HQ: San Francisco, CA, United States
Sweep
Hiring
What they do:
The best AI coding assistant for JetBrains
Quick facts:
HQ: San Francisco, CA, United States
DryMerge
Hiring
What they do:
AI that updates your CRM for you
Quick facts:
HQ: San Francisco, CA, United States
Duckie
Hiring
What they do:
Build AI Support Agents in Minutes
Quick facts:
HQ: San Francisco, CA, United States
Newton
Hiring
What they do:
AI-powered phone platform for dentists
Quick facts:
HQ: San Francisco, CA, United States
JustAI
Hiring
What they do:
Agentic Marketing Platform
Quick facts:
HQ: San Francisco, CA, United States
Brainbase Labs
Hiring
What they do:
The AI Labor Company
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-voice agents that are indistinguishable from humans.
Quick facts:
HQ: San Francisco, CA, United States
Cloudglue
Hiring
What they do:
The video context layer for AI.
Quick facts:
HQ: San Francisco, CA, United States
Outerport
Hiring
What they do:
Design automation for industrial electrical controls
Quick facts:
HQ: San Francisco, CA, United States
Onlook
Hiring
What they do:
The Developer tool for Designers
Quick facts:
HQ: San Francisco, CA, United States
Openbenchmarks
Hiring
What they do:
We help humans & agents pick tools via Independent Benchmarks
Quick facts:
HQ: San Francisco, CA, United States