What they do:
Reimagining how Machines Learn
Quick facts:
HQ: San Francisco, CA, United States
YC W25Early stage
Top B2B Software Startups in California
This list has 2,349 startups and was last updated on Oct 15, 2026. 592 of them are hiring right now. Biggest hubs: San Francisco (2,110), Los Angeles (79), and San Diego (12). Largest teams: Stripe, Deel, and GrubMarket. Latest round: Modal raised $750M (Oct 14, 2026).
2,349 startupsPage 42 of 66
What they do:
Accelerating world models.
Quick facts:
HQ: San Francisco, CA, United States
YC X25Early stage
What they do:
Explore dozens of design directions with your agent
Quick facts:
HQ: San Francisco, CA, United States
YC F25Early stage
What they do:
AI Document Workflows for Enterprises
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HQ: San Francisco, CA, United States
YC W26Early stage
What they do:
AI-native back-office for banks and fintechs
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
AI Event Manager for in-person events
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HQ: San Francisco, CA, United States
YC X26Early stage
What they do:
AI Employee for Manufacturing Operations
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HQ: San Francisco, CA, United States
YC X26Early stage
What they do:
Engineering Intelligence and Token Optimization for the AI-Coding Era
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
We help Fortune 500 companies hedge their supply chain risk
Quick facts:
HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
AI-native insurance department for auto body shops
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HQ: San Francisco, CA, United States
YC W27Early stage
What they do:
Teaching AI to Design Chips
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Autonomous Hardware Testing
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
AI teammates for your business-critical work.
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
AI-native Accounting Firm that's killing Deloitte
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Resin helps engineers design electronics faster and more reliably
Quick facts:
HQ: San Francisco, CA, United States
YC F26Early stage
What they do:
A graph based IDE for when agents program faster than you can read
Quick facts:
HQ: San Francisco, CA, United States
YC F26Early stage
What they do:
The crowdsourced benchmark for AI-generated music and music production
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HQ: San Francisco, CA, United States
Optimizely
Acquired
What they do:
The first all-in-one operating system for marketing
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HQ: San Francisco, CA, United States
Segment
Acquired
What they do:
Software and APIs to collect, clean, and control customer data.
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HQ: San Francisco, CA, United States
Heroku
Acquired
What they do:
Enabling developers to build and run applications in the cloud.
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HQ: San Francisco, CA, United States
Lever
Acquired
What they do:
Talent Acquisition Suite that combines ATS + Talent CRM
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HQ: San Francisco, CA, United States
Clever
Acquired
What they do:
The platform that powers technology in the classroom.
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HQ: San Francisco, CA, United States
Fivestars
Acquired
What they do:
Customer loyalty and payments platform for small businesses.
Quick facts:
HQ: San Francisco, CA, United States
Weebly
Acquired
What they do:
Build a free website that grows with your business.
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HQ: San Francisco, CA, United States
DrChrono
Acquired
What they do:
The essential platform for modern medical practices and patients.
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HQ: San Francisco, CA, United States
CoreOS
Acquired
What they do:
Open source tools of modern distributed systems.
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HQ: San Francisco, CA, United States
Sqreen
Acquired
What they do:
Sqreen is the application security platform for the modern enterprise
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HQ: San Francisco, CA, United States
HelloSign
Acquired
What they do:
eSignature software for small and mid-market businesses.
Quick facts:
HQ: San Francisco, CA, United States
Quick facts:
HQ: San Francisco, CA, United States
Funding:
$1.1B · Equity · Jun 2026
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HQ: San Diego, CA, United States
Funding:
$592M · Equity · May 2026
Quick facts:
HQ: Mountain View, CA, United States
Incorporated: 2023
Funding:
$528M · Equity · Mar 2026
Quick facts:
HQ: San Francisco, CA, United States
Incorporated: 2023
Funding:
$435M · Equity · Jan 2026
Quick facts:
HQ: San Francisco, CA, United States
Incorporated: 2024
Funding:
$364M · Equity · Jun 2026
Quick facts:
HQ: San Francisco, CA, United States
Incorporated: 2022
Funding:
$330M · Equity · Feb 2026
Quick facts:
HQ: San Carlos, CA, United States
Incorporated: 2023
Funding:
$305M · Equity · May 2026
Quick facts:
HQ: Palo Alto, CA, United States
Incorporated: 2022
Funding:
$275M · Equity · Jan 2026