Pulse
Hiring
What they do:
Production-grade unstructured document extraction
Quick facts:
HQ: San Francisco, CA, United States
Top B2B Software Startups in California
This list has 2,349 startups and was last updated on Oct 15, 2026. 592 of them are hiring right now. Biggest hubs: San Francisco (2,110), Los Angeles (79), and San Diego (12). Largest teams: Stripe, Deel, and GrubMarket. Latest round: Modal raised $750M (Oct 14, 2026).
2,349 startupsPage 8 of 66
What they do:
Environments as a service
Quick facts:
HQ: Los Angeles, CA, United States
IOMETE
Hiring
What they do:
Self-hosted data lakehouse platform
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HQ: San Francisco, CA, United States
Strada
Hiring
What they do:
AI agents that run insurance operations
Quick facts:
HQ: San Francisco, CA, United States
Castle
Hiring
What they do:
Block bots & bad behavior
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HQ: San Francisco, CA, United States
What they do:
Just-in-time training and communication for frontline healthcare teams
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HQ: San Francisco, CA, United States
Nestor
Hiring
What they do:
Skills-based talent management solutions for a dynamic workforce.
Quick facts:
HQ: San Francisco, CA, United States
Accord
Hiring
What they do:
The Revenue Excellence Platform
Quick facts:
HQ: San Francisco, CA, United States
Swif.ai
Hiring
What they do:
Manage every device. Govern every AI agent.
Quick facts:
HQ: San Francisco, CA, United States
Serif Health
Hiring
What they do:
Healthcare Price Transparency APIs and Data Products
Quick facts:
HQ: Los Angeles, CA, United States
Replo
Hiring
What they do:
Sell anything
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HQ: San Francisco, CA, United States
OneSchema
Hiring
What they do:
The AI Cowork for big data
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HQ: San Francisco, CA, United States
What they do:
We make Orca, MIT open source terminal-based agent orchestrator
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HQ: San Francisco, CA, United States
Medplum
Hiring
What they do:
API first electronic health record (EHR) that is open source
Quick facts:
HQ: San Francisco, CA, United States
loopfour
Hiring
What they do:
Workflow automation, without AI hallucinations.
Quick facts:
HQ: San Francisco, CA, United States
LiteLLM
Hiring
What they do:
Call every LLM API like it's OpenAI [100+ LLMs]
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HQ: San Francisco, CA, United States
Artie
Hiring
What they do:
Software that streams data from databases to warehouses in real-time
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HQ: San Francisco, CA, United States
Readily
Hiring
What they do:
AI Compliance Platform for Healthcare Organizations
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HQ: San Francisco, CA, United States
FleetWorks
Hiring
What they do:
AI enabled marketplace matching trucks with jobs
Quick facts:
HQ: San Francisco, CA, United States
Tamarind Bio
Hiring
What they do:
AI Inference Platform for Drug Discovery
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Frontier coding data for training and evaluating LLMs
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HQ: San Francisco, CA, United States
Contrario
Hiring
What they do:
AI hiring platform powered by expert recruiters
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HQ: San Francisco, CA, United States
What they do:
The easiest way to set up a modern data stack
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HQ: San Francisco, CA, United States
What they do:
The fastest way to ship airtight AI
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HQ: San Francisco, CA, United States
Merlin AI
Hiring
What they do:
AI powered ERP for Construction
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HQ: Los Angeles, CA, United States
JITX
Hiring
What they do:
Automatic circuit board design.
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HQ: San Francisco, CA, United States
What they do:
The funnel builder built for health & wellness brands.
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HQ: San Francisco, CA, United States
What they do:
The fashion product engineering intelligence
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HQ: San Francisco, CA, United States
Eventual
Hiring
What they do:
Building the AI data engine for any modality and scale
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HQ: San Francisco, CA, United States
Inkeep
Hiring
What they do:
Build AI Agent teammates and automations in code or no-code
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HQ: San Francisco, CA, United States
What they do:
AI edited video souvenirs as a service
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HQ: San Francisco, CA, United States
What they do:
Develop your CI/CD pipelines as code and run them anywhere
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HQ: San Francisco, CA, United States
Topkey
Hiring
What they do:
Topkey is the all-in-one financial operating platform that simplifies expense management for hospitality managers.
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HQ: San Francisco, CA, United States
What they do:
Crazy fast, open source infra for AI agents to use the Internet
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HQ: San Francisco, CA, United States
Slope
Hiring
What they do:
The B2B Payments Platform
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HQ: San Francisco, CA, United States
Oway
Hiring
What they do:
Building the open operating system for the automated physical economy.
Quick facts:
HQ: San Francisco, CA, United States